2 5-Dimethylpyrazine (CAS 123-32-0): A Flavor Chemistry Perspective for Procurement and Formulation Teams

2 5-Dimethyl pyrazine
Get One-Stop Solution from This Page
 There is a moment in roasting coffee when the beans shift from pale yellow-green to light brown and the aroma in the room changes completely — from grassy and raw to nutty, roasted, almost caramel-like. Pyrazines are responsible. And 2 5-Dimethylpyrazine (CAS 123-32-0) is among the compounds that show up reliably in that flavor transition.
 
This six-membered aromatic ring with two nitrogen atoms and two methyl groups at the 2 and 5 positions is a Maillard reaction product — it forms when sugars and amino acids react under heat. It shows up in roasted meat, baked bread, popcorn, coffee, peanuts, and dozens of other thermally processed foods. In flavor formulations, it is used to build roasted and nutty top notes that read as natural because, technically, they occur naturally.

Purity Specifications for Flavor-Grade Material

2 5-Dimethylpyrazine for flavor use is available at several purity tiers. The compound itself (MW 108.14, bp approximately 155 degrees Celsius, density around 0.990 g/cm3) is relatively stable under normal storage conditions, which makes handling and shipping straightforward compared to more reactive aroma chemicals.
 
For most flavor applications, 98% GC purity is the working standard. The impurities that matter most are structural isomers — 2,3-dimethylpyrazine and 2,6-dimethylpyrazine — which have different odor characters and can shift the roasted note toward unwanted directions. A CoA that reports “98% dimethylpyrazine” without specifying the isomer or identifying the main impurities is not providing enough information for a careful flavor chemist to make an informed purchase decision.
 
Ask suppliers specifically: what isomers are present and at what levels? This question alone filters suppliers by how seriously they run their analysis.

Usage and Application Context

In flavor work, 2 5-Dimethylpyrazine is used at low concentrations — typically in the range of 1 to 50 ppm in the finished food product, depending on application. At higher levels it can become overpowering and harsh; the art is in using it as part of a pyrazine blend that together builds a rounded roasted profile rather than a single sharp note.
 
Beyond flavors, the compound finds use in pharmaceutical synthesis as a building block and in agrochemical research. In these contexts, purity requirements shift from odor profile to chemical identity and reactive impurity control, and documentation expectations are substantially more rigorous.
 
Procurement teams ordering for pharmaceutical or agrochemical applications should specify these requirements explicitly and ask for GC-MS data and process-related impurity analysis, not just standard flavor-grade documentation.

Import and Regulatory Considerations

2 5-Dimethylpyrazine holds FEMA GRAS status (FEMA 3272) in the United States and appears on the EU Union List of flavoring substances (FL 14.085). These approvals support use in food applications across the major markets.
 
The compound is a solid at room temperature (melting point approximately 15 degrees Celsius means it can solidify in cold storage or transit — verify with your supplier whether the material you receive may need gentle warming before use). This physical behavior sometimes surprises buyers who are not familiar with the compound, and it is worth confirming the melting point and expected physical state at ambient temperature in your warehouse before placing a large first order.
2 5-Dimethyl pyrazine

What ZhishangChem Offers

ZhishangChem manufactures 2 5-Dimethylpyrazine for flavor, pharmaceutical, and industrial customers. Batch CoA includes GC purity with isomer identification, GC-MS identity confirmation, physical constants (melting point, appearance), and a GHS-compliant SDS. Complete export documentation for EU, US, Japan, and other major markets is standard.
 
Minimum order 1 kg. Bulk pricing above 5 kg. Standard packaging in amber glass or HDPE containers. Lead time is typically 5 to 10 business days for standard stock material.
 
For technical questions, application-specific grade selection, or sample requests, contact sales001@sdzschem.com.
 

Related News Recommendations

Our Factory Equipment

标签：无