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p-Menthane-3,8-diol (PMD) CAS 42822-86-6 DEET-Free Repellent Ingredient

p-Menthane-3,8-diol (PMD) CAS 42822-86-6 Manufacturer | Zhishang Chem
  • Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
  • Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
  • Min: 10 Gram
  • Delivery: 10 Days
  • Transporta: Ocean, Land,Air, DHL,TNT
  • Port: Shanghai Port, Qingdao Port

Name: p-Menthane-3,8-diol

Cas: 42822-86-6

Purity: 99%

MOQ: 1KG

Basic Info

p-Menthane-3,8-diol (CAS Registry Number: 42822-86-6), widely referred to as PMD or menthanediol, is a monoterpenoid diol recognized globally as one of the most effective non-synthetic active ingredients for biting insect protection. Structure-wise, PMD features two hydroxyl groups anchored to a p-menthane carbon skeleton (C₁₀H₂₀O₂), existing naturally in small concentrations within the leaves of Corymbia citriodora (Lemon Eucalyptus) and synthesized via controlled cyclization of citronellal.
 
At Shandong Zhishang Chem Co., Ltd., we manufacture and export high-purity PMD tailored for liquid sprays, creams, lotions, and wearable repellent devices. Operating with balanced cis/trans isomer ratios, our PMD grade delivers exceptional vapor-phase spatial shielding against mosquitoes, midges, and ticks while presenting a low dermal irritation profile compared to conventional synthetic repellents.
Specification ParameterStandard RequirementTest Standard / Method
CAS Registry Number42822-86-6EC No: 255-953-7 / INCI: Menthane-3,8-diol
Chemical Name2-(2-hydroxypropan-2-yl)-5-methylcyclohexan-1-olIUPAC Nomenclature
Molecular Formula / WeightC₁₀H₂₀O₂172.27 g/mol
Active Purity (Total Isomers)≥ 98.0%Gas Chromatography (GC-FID)
Cis / Trans Isomer Ratio60:40 to 70:30 (Optimized Efficacy)GC Peak Integration
Physical Appearance (25°C)Colorless to pale yellow crystalline solid or viscous liquidVisual Inspection
Odor ProfileMild, sweet, cooling minty-eucalyptus scentSensory Evaluation
Melting Point Range40°C – 45°CCapillary Melting Apparatus
Solubility ProfileSoluble in Ethanol, Isopropanol, Glycols; Sparingly soluble in waterGravimetric Assessment

Product Packaging

p-Menthane-3,8-diol’s unique vapor pressure and pleasant olfactory profile make it a preferred functional choice across personal care and pest management sectors:
 
DEET-Free Mosquito Repellent Sprays: Serves as the primary active ingredient (typically formulated at 10% to 30% concentration) providing multi-hour protection against Aedes, Anopheles, and Culex mosquito species.
 
Tick & Midge Defense Lotions: Blended into emulsion creams and sunscreens to offer broad-spectrum defense against ticks, blackflies, and land leeches during outdoor activities.
 
Wearable & Solid Repellent Devices: Impregnated into polymer wristbands, gel patches, and slow-release spatial diffusers for continuous outdoor protection.
 
Soothing After-Bite Topical Additive: Incorporates into cooling gels and balm sticks due to its mild intrinsic cooling sensation on skin.

FAQ

A: PMD is widely recognized as the only plant-derived active ingredient with repellent protection times comparable to synthetic DEET. Unlike DEET, PMD does not melt plastics or synthetic fabrics, features a pleasant herbal mint aroma, and is generally preferred for sensitive skin and family-friendly formulations.

A: Pure PMD has low water solubility. To formulate clear water-based sprays, PMD should be pre-dissolved in ethanol or combined with non-ionic solubilizers (such as Polysorbate 20 or PEG-40 Hydrogenated Castor Oil) before mixing into the water phase.

A: PMD should be stored in original, tightly sealed drums in a cool, dry, well-ventilated warehouse away from direct sunlight and heat sources (recommended storage temperature: 15°C to 25°C). Avoid prolonged exposure to air to prevent moisture absorption.

A: We supply PMD in 25 kg fiber drums lined with double PE bags, 50 kg plastic drums, or 200 kg steel drums for high-volume manufacturers. Each shipment includes a batch-specific Certificate of Analysis (COA), Safety Data Sheet (SDS), and technical support for custom formulation development.

Related References

Pubchem-p-Menthane-3,8-diol

Chemicalbook-p-Menthane-3,8-diol

Regulatory Compliance & Global Certifications

Navigating global biocide regulations requires rigid quality tracking. Shandong Zhishang Chemical provides comprehensive compliance support to streamline your brand’s regional registration:

  • ISO 9001:2015 Certification: Enforces strict quality management protocols across raw material selection, catalytic transformation, distillation, and nitrogen-sealed filling.

  • EPA & EU Biocidal Products Regulation (BPR) Data Support: Our PMD technical data aligns with guidelines established by major environmental protection frameworks for registered active substances.

  • REACH Compliance Documentation: Complete analytical dossiers available for European Union importers and downstream formulators.

  • Cruelty-Free & Sustainable Origin Verification: Processed without animal testing, utilizing renewable terpene feedstocks to satisfy consumer demand for clean-label insect repellents.

Because insect repulsion performance depends heavily on structural isomer distribution and low impurity thresholds, each export production lot of p-Menthane-3,8-diol undergoes four-step laboratory verification before Certificate of Analysis (COA) release:

  1. GC-FID Isomer Quantification: Measures total purity (≥ 98.0%) and verifies the specific ratio of cis-PMD and trans-PMD to guarantee optimal vapor evaporation rates.

  2. Residual Isopulegol & Citronellal Assay: Limits unreacted terpene precursors (Isopulegol < 0.5%, Citronellal < 0.2%) via gas chromatography to minimize potential skin sensitization risks.

  3. Heavy Metal Trace Analysis (ICP-OES): Confirms Lead (< 5 ppm) and Arsenic (< 1 ppm) remain well below global cosmetic and personal safety limits.

  4. Thermogravimetric Loss on Drying: Checks moisture and volatile organic solvent residues to maintain clear dissolution when diluted into alcohol-based or aqueous lotion systems.

Manufacturer of p-Menthane-3,8-diol

Company Info

ZhishangChem company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

Cooperation Partner

Raymond
I would like to thank Shandong Zhishang New Materials Co., Ltd. for a very efficient transaction with their team.
Happy cooperation
Raymond Louis
The goods have been delivered intact. good packing. honest seller
Very satisfied
Mary
As usual, a great service from dear zhishang chemical, and the perfect quality of product! Highly recommend this company, and hope for long and productive cooperation :)
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