Name: 18β-Glycyrrhetinic Acid
Cas: 471-53-4
Purity: 99%
MOQ: 1KG
Directory Guidance on 18β-Glycyrrhetinic Acid
Chemical Structure

Basic Info
18β-Glycyrrhetinic Acid is a natural triterpenoid compound mainly extracted from the roots of licorice. Its molecular formula is C30H46O7, and its chemical structure consists of a glycyrrhizic acid moiety and a sugar moiety. It has significant biological activities such as antioxidant, anti-inflammatory, and antiviral. 18β-Glycyrrhetinic Acid is widely used in cosmetics, pharmaceuticals, and food industries, especially as an effective ingredient for whitening, anti-inflammatory, and soothing the skin in cosmetics. It can inhibit melanin production, reduce skin inflammation, and improve uneven skin color. It is commonly used in various skin care products, such as face creams, essences and sunscreen.
Product Introduction
| Melting point | 292-295 °C(lit.) |
| alpha | 165 º (c=1, CHCl3,on dry ba) |
| Boiling point | 492.11°C (rough estimate) |
| density | 0.9967 (rough estimate) |
| vapor pressure | 10-220Pa at 20-50℃ |
| refractive index | 162 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride. |
| pka | pKa 5.56±0.1 (Uncertain) |
| form | Crystalline Powder |
| color | White to off-white |
| optical activity | [α]22/D +170.0°, c = 1 in chloroform |
| Water Solubility | SOLUBLE IN ACETIC ACID |
| MF: | C30H46O4 |
| MW: | 470.69 |
| EINECS: | 207-444-6 |
| Item | Specification |
| Product Name | 18β-Glycyrrhetinic Acid |
| CAS No. | 471-53-4 |
| Appearance | liquid |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Cosmetics and skincare products
The application of 18β-Glycyrrhetinic Acid in cosmetics is particularly prominent, mainly as an effective ingredient for whitening, anti-inflammatory, antioxidant, and soothing the skin. It improves uneven skin tone and reduces pigmentation by inhibiting tyrosinase activity and reducing melanin production. In addition, 18β-Glycyrrhetinic Acid also has anti-inflammatory effects, which can alleviate skin allergies, redness, and inflammation, making it suitable for sensitive skin care. Common application products include whitening essences, anti-aging face creams, eye creams, sunscreen, etc.
2. Drugs and health products
18β-Glycyrrhetinic Acid has significant anti-inflammatory, antiviral, anti-allergic, and immune regulatory functions and is widely used in medicine. It is commonly used to treat allergic diseases, digestive system problems (such as gastritis and gastric ulcers), and liver diseases. 18β-Glycyrrhetinic Acid has also been used to prepare some health products with immune-enhancing effects. It can enhance the body’s ability to fight against viruses, reduce inflammatory reactions, and play an auxiliary role in antiviral therapy.
3. Food additives
In the food industry, 18β-Glycyrrhetinic Acid can be used as a natural sweetener and preservative. Its sweetness is 50 times that of sucrose but does not contain calories, so it is often used in low-calorie foods and beverages. In addition, 18β-Glycyrrhetinic Acid also has antioxidant properties, can extend the shelf life of food, and is used as a flavor ingredient. Its natural origin and safety make it an ideal food additive.
4. Agriculture and Plant Protection
18β-Glycyrrhetinic Acid also has applications in agriculture, especially in plant protection. It has certain antibacterial and antifungal effects and can be used as a natural plant protectant to help improve crop disease resistance. In addition, 18β-Glycyrrhetinic Acid has been studied as a natural pesticide substitute with low toxicity and environmental friendliness, suitable for promoting organic and green agriculture.
5. Other fields
18β-Glycyrrhetinic Acid has also been studied for use in various other fields, such as a natural antioxidant added to cosmetic packaging materials or as an ingredient that promotes skin cell regeneration in the field of skin repair. In addition, 18β-Glycyrrhetinic Acid has been widely used in traditional Chinese medicine, often as a combination ingredient in prescriptions to treat symptoms such as cough, sore throat, and excessive phlegm.
Related References
Manufacturer of 18β-Glycyrrhetinic Acid
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 18β-Glycyrrhetinic Acid manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





