Name: 2-Fluorocinnamic Acid
Cas: 451-69-4
Purity: 99%
MOQ: 1KG
Directory Guidance on 2-Fluorocinnamic Acid
Chemical Structure

Basic Info
2-Fluorocinnamic acid, chemical name is 3-(2-fluorophenyl)-2-propenoic acid, molecular formula is C₉H₇FO₂, molecular weight is 166.15, CAS number is 451-69-4. It is a white to off-white crystalline powder with a melting point of 178-180°C, a boiling point of about 281.6°C (normal pressure), and a density of about 1.3 g/cm³. The compound is insoluble in water, but soluble in organic solvents such as ethanol and ethyl acetate. Its chemical properties are relatively stable, but it needs to avoid contact with oxidants138.
The structure of 2-Fluorocinnamic acid contains a benzene ring, an acrylic acid group and an ortho-fluorine substituent, which makes it have the reaction characteristics of both aromatic compounds and carboxylic acids. Its trans isomer (E form) is the main form of existence, which can be characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR) and other methods. The compound needs to be sealed and stored in a cool and dry place at room temperature to prevent moisture absorption or decomposition.
Product Introduction
| Melting point | 178-180 °C(lit.) |
| Boiling point | 290°C (rough estimate) |
| density | 1.2247 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Crystalline Powder of Flakes |
| pka | 4.31±0.10(Predicted) |
| color | White |
| MF: | C9H7FO2 |
| MW: | 166.15 |
| EINECS: | 207-195-3 |
| Item | Specification |
| Product Name | 2-Fluorocinnamic Acid |
| CAS No. | 451-69-4 |
| Appearance | Powder |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Intermediates in the synthesis of antitumor, anti-inflammatory and cancer drugs
2-Fluorocinnamic Acid, an important pharmaceutical intermediary, is used to synthesize anti-tumor drugs and anti-inflammatory or cardiovascular drugs. Its molecular structure, which contains fluorine and acrylic acid groups, can increase the biological activity and metabolism stability of the drug. For example, in the development of anti-tumor drugs, o-fluorocinnamic acid derivatives can play an anti-cancer role by inhibiting cancer cell proliferation-related signaling pathways (such as NF-kB). It can also be synthesized into non-steroidal antiinflammatory drugs (NSAIDs), which reduce inflammation by regulating cyclooxygenase activity.
2. Liquid crystal materials (high-performance display devices)
Due to their excellent thermal and electrical stability, high-end TFT materials are made from fluorinated cinnamic acids (such as p -fluorocinnamic) in the LCD industry. The 2-Fluorocinnamic Acid has a similar potential. Its molecular structures can be used to reduce the viscosity in liquid crystals, to increase response time (to less than 16ms), to widen the temperature range of operation (-20 to 50 degrees), making it suitable for display screens like smartphones and TVs.
3. Photosensitive Materials (Green Printing and Imaging Technology)
2-Fluorocinnamic Acid, a photosensitive raw material for the printing industry, is a brand new product. It is highly sensitive, has rapid photolysis, and is environmentally friendly. It can be used to replace silver-containing materials that are traditionally used for photosensitive materials, and it reduces heavy metal pollution. Its photosensitivity makes it suitable for digital printing and PS plates, while also meeting green printing standards and improving color saturation and imaging resolution. Its high radiation resistance and stability make it a perfect photosensitive material for aerospace optical systems.
4. Organic Synthesis (fine chemicals and functional materials)
As a building block for organic synthesis, 2-Fluorocinnamic acid can be used to make polymer materials such as flame retardants, zinc plating corrosion inhibitors and epoxy resin modifiers. The fluorine in its structure increases the mechanical strength and weather resistance of polymers. It is also suitable for automotive coatings and electronic packaging materials. It can be used in asymmetric reactions as a chiral catalyst ligand.
5. Flavors and fragrances
While 2-Fluorocinnamic Acid has a mild aroma, its esters (such as those used in coffee and meat flavors) as well as everyday chemical products (perfumes and skin care products) can fixate the flavor of food (such a coffee or meat flavors). The fluorine structure is able to prolong the scent and improve the UV absorption, making it suitable for sunscreen formulations.
6. Preservatives and pesticides (agriculture and food preservation)
Its antibacterial properties make 2-Fluorocinnamic Acid a component of pesticides that prevent and control fungal diseases in crops. In the food and beverage industry, derivatives of 2-Fluorocinnamic Acid (such as potassium Cinnamate) are used to replace sodium benzoate in fruit and vegetable preservation.
Related References
As a company specializing in the production and supply of 2-Fluorocinnamic acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required 2-Fluorocinnamic acid raw materials to support your production and research and development.
We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.
Manufacturer of 2-Fluorocinnamic Acid
Zhishang Chem is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 2-Fluorocinnamic Acid manufacturer, Zhi shang Chem has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





