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Manufacturer 2-Fluorocinnamic Acid CAS 451-69-4

  • Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
  • Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
  • Min: 10 Gram
  • Delivery: 7 Days
  • Transporta: Ocean, Land,Air, DHL,TNT
  • Port: Shanghai Port, Qingdao Port

Name: 2-Fluorocinnamic Acid

Cas: 451-69-4

Purity: 99%

MOQ: 1KG

Basic Info

2-Fluorocinnamic acid, chemical name is 3-(2-fluorophenyl)-2-propenoic acid, molecular formula is C₉H₇FO₂, molecular weight is 166.15, CAS number is 451-69-4. It is a white to off-white crystalline powder with a melting point of 178-180°C, a boiling point of about 281.6°C (normal pressure), and a density of about 1.3 g/cm³. The compound is insoluble in water, but soluble in organic solvents such as ethanol and ethyl acetate. Its chemical properties are relatively stable, but it needs to avoid contact with oxidants138.

The structure of 2-Fluorocinnamic acid contains a benzene ring, an acrylic acid group and an ortho-fluorine substituent, which makes it have the reaction characteristics of both aromatic compounds and carboxylic acids. Its trans isomer (E form) is the main form of existence, which can be characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR) and other methods. The compound needs to be sealed and stored in a cool and dry place at room temperature to prevent moisture absorption or decomposition.

Product Introduction

Melting point 178-180 °C(lit.)
Boiling point 290°C (rough estimate)
density 1.2247 (estimate)
storage temp. Inert atmosphere,Room Temperature
form Crystalline Powder of Flakes
pka4.31±0.10(Predicted)
color White

 

Product Packaging

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1. Intermediates in the synthesis of antitumor, anti-inflammatory and cancer drugs
2-Fluorocinnamic Acid, an important pharmaceutical intermediary, is used to synthesize anti-tumor drugs and anti-inflammatory or cardiovascular drugs. Its molecular structure, which contains fluorine and acrylic acid groups, can increase the biological activity and metabolism stability of the drug. For example, in the development of anti-tumor drugs, o-fluorocinnamic acid derivatives can play an anti-cancer role by inhibiting cancer cell proliferation-related signaling pathways (such as NF-kB). It can also be synthesized into non-steroidal antiinflammatory drugs (NSAIDs), which reduce inflammation by regulating cyclooxygenase activity.

2. Liquid crystal materials (high-performance display devices)
Due to their excellent thermal and electrical stability, high-end TFT materials are made from fluorinated cinnamic acids (such as p -fluorocinnamic) in the LCD industry. The 2-Fluorocinnamic Acid has a similar potential. Its molecular structures can be used to reduce the viscosity in liquid crystals, to increase response time (to less than 16ms), to widen the temperature range of operation (-20 to 50 degrees), making it suitable for display screens like smartphones and TVs.

3. Photosensitive Materials (Green Printing and Imaging Technology)
2-Fluorocinnamic Acid, a photosensitive raw material for the printing industry, is a brand new product. It is highly sensitive, has rapid photolysis, and is environmentally friendly. It can be used to replace silver-containing materials that are traditionally used for photosensitive materials, and it reduces heavy metal pollution. Its photosensitivity makes it suitable for digital printing and PS plates, while also meeting green printing standards and improving color saturation and imaging resolution. Its high radiation resistance and stability make it a perfect photosensitive material for aerospace optical systems.

4. Organic Synthesis (fine chemicals and functional materials)
As a building block for organic synthesis, 2-Fluorocinnamic acid can be used to make polymer materials such as flame retardants, zinc plating corrosion inhibitors and epoxy resin modifiers. The fluorine in its structure increases the mechanical strength and weather resistance of polymers. It is also suitable for automotive coatings and electronic packaging materials. It can be used in asymmetric reactions as a chiral catalyst ligand.

5. Flavors and fragrances
While 2-Fluorocinnamic Acid has a mild aroma, its esters (such as those used in coffee and meat flavors) as well as everyday chemical products (perfumes and skin care products) can fixate the flavor of food (such a coffee or meat flavors). The fluorine structure is able to prolong the scent and improve the UV absorption, making it suitable for sunscreen formulations.

6. Preservatives and pesticides (agriculture and food preservation)
Its antibacterial properties make 2-Fluorocinnamic Acid a component of pesticides that prevent and control fungal diseases in crops. In the food and beverage industry, derivatives of 2-Fluorocinnamic Acid (such as potassium Cinnamate) are used to replace sodium benzoate in fruit and vegetable preservation.

Related References

As a company specializing in the production and supply of 2-Fluorocinnamic acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required 2-Fluorocinnamic acid raw materials to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Manufacturer of 2-Fluorocinnamic Acid

Company Info

Zhishang chem company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

Cooperation Partner

Raymond
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