Name: 2,4,5-Trimethylthiazole
Cas: 13623-11-5
Purity: 99%
MOQ: 1KG
Directory Guidance on 2,4,5-Trimethylthiazole
Nature and Specifications
| MF: | C6H9NS |
| MW: | 127.21 |
| EINECS: | 237-107-9 |
Basic Info
2,4,5-Trimethylthiazole is a sulfur-containing five membered heterocyclic compound, whose core structure consists of a thiazole ring containing four carbon atoms, one sulfur atom, and one nitrogen atom, forming a stable five membered cyclic structure. Methyl (- CH3) substituents are attached to positions 2, 4, and 5 of the ring. This specific substitution pattern not only affects the chemical name of the compound, but also its spatial structure and electronic distribution.
From a physical property perspective, 2,4,5-Trimethylthiazole typically appears as a colorless to pale yellow liquid, possessing unique intermolecular forces that give it a specific boiling point and density. Chemically, the thiazole has a degree of aromaticity. The addition of three methyl groups regulates the density of electron clouds in the ring. This makes it different from other methyl substituted compounds and simple thiazoles. This structure is characterized by its stability and reactivity, which makes it an important class of heterocyclic compound with research value.
Product Introduction
| Melting point | -32.4°C |
| Boiling point | 166-167 °C/717 mmHg (lit.) |
| density | 1.013 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.509(lit.) |
| FEMA | 3325 | 2,4,5-TRIMETHYLTHIAZOLE |
| Fp | 133 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | pK1:4.55 (25°C,μ=0.1) |
| form | liquid |
| Specific Gravity | 1.311.013 |
| color | Light orange to Yellow to Green |
| Odor | at 1.00 % in dipropylene glycol. musty nutty vegetable cocoa hazelnut chocolate coffee |
| Odor Type | chocolate |
⇒We provide high-purity chemical raw materials with clear molecular formula and precise specifications. Each batch of 2,4,5-Trimethylthiazole products undergoes strict quality inspection to ensure stable and reliable physical and chemical properties. It adopts international standard packaging, sealed and moisture-proof, to ensure safe transportation and storage. Whether it is R&D experiments or industrial production, we can provide you with professional technical support and customized services. With rigorous technology, transparent data and stable supply, we help you efficiently complete chemical applications and innovations.

Chemical Analysis
2,4,5-Trimethylthiazole, due to its low volatility and strong chemical inertness, has become an ideal internal standard for the determination of aldehyde substances in alcoholic beverages by gas chromatography. It can complete the extraction and seperation process of aldehyde compounds in complex sample matrixes without reacting to these components, such as the malt aroma components found in beer, tannin substances present wine or polyol systems of white liquor. This eliminates interference from matrix effects such as the adsorption of active components or their transformation in the sample that can affect the determination of the aldehydes. It provides a stable, repeatable reference for the accurate quantification of aldehyde compounds such as propionaldehyde or acetaldehyde.


Fragrance & Flavor
The sulfur-containing ring structure of 2,4,5-Trimethylthiazole and the synergistic effect of the methyl substituents make its emitted odor rich in layers and highly recognizable. The odor of 2,4,5-Trimethylthiazole is stable under different pH and temperature levels. This can be useful for perfumes or food processing environments where skin reactions to acid-base changes are common. A low-odor threshold can simulate the fragrance to imitate tropical fruits like pineapple and mango. The fragrance is also enhanced by floral components. Additions of 0.1% to 0.5 % in perfume formulations can create complex aromas with distinct front, middle, and back notes.
Materials Science Field
When 2,4,5-Trimethylthiazole is used as a photoinitiator, it has high sensitivity to ultraviolet light. It can decompose in the presence of ultraviolet light between wavelengths 250nm-365nm, resulting in free radicals. It can be used to trigger the polymerization in monomers such as acrylic acid or epoxy resin within a short period of time, which can decrease the curing times by 30%.


Medical Research and Life Sciences
Although the direct application of 2,4,5-Trimethylthiazole is still in the exploration stage, its unique molecular configuration with a sulfur-containing ring and methyl substituents provides valuable structural templates for drug molecule design. Its structure makes it soluble in fats. This allows it pass through cell membranes and enter the cell’s interior, where it can interact with biological targets. Compounds with similar structures have been shown to bind to biological targets. They can bind to the active centers of enzymes to block their function, or to receptors that control signal transmission. Similar structures are used in antibacterial research to disrupt bacterial cell walls. In antitumor studies, they block the signaling pathways of tumor cells.
Related References
Manufacturer of 2,4,5-Trimethylthiazole
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 2,4,5-Trimethylthiazole manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.






