Name: 4-Fluorocinnamic Acid
Cas: 459-32-5
Purity: 99%
MOQ: 1KG
Directory Guidance on 4-Fluorocinnamic Acid
Chemical Structure

Basic Info
4-Fluorocinnamic Acid, chemical name is 3-[(4-fluoro)phenyl]-2-acrylic acid, which is white crystal. It is used widely in the printing, medical, liquid crystal, and electroplating industries. As a pharmaceutical synthesis intermediary, 4-fluorocinnamic is an excellent product. It can also be used as an electroplating brightness enhancer, which compensates for the fact that the main brightener only brightens within a specific range of current density.
Due to its low molecular weight, 4-Fluorocinnamic Acid is able to work at any temperature, it has a high photosensitivity and possesses a short response time. It also has permeability that is good, allowing liquid crystal displays luminous brightness and saturation.
Product Introduction
| Melting point | 209-210 °C (lit.) |
| Boiling point | 290°C (rough estimate) |
| density | 1.2247 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Crystalline Solid |
| pka | 4.43±0.10(Predicted) |
| color | White to off-white |
| MF: | C9H7FO2 |
| MW: | 166.15 |
| EINECS: | 207-288-9 |
| Item | Specification |
| Product Name | 4-Fluorocinnamic Acid |
| CAS No. | 459-32-5 |
| Appearance | liquid |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Pharmaceutical industry
1. Drug synthesis intermediate
4-Fluorocinnamic Acid can be used to synthesize a wide range of drugs, including:
NSAIDs (non-steroidal antiinflammatory drugs): its structure can be used for the synthesizing of anti-inflammatory and analgesic drug substituted with fluorine.
Antitumor drugs – Fluorine atoms improve the bioavailability of drugs by improving their metabolic stability. Some derivatives are able to inhibit the growth of cancer cells.
Antibacterial/antiviral agents: Fluorine-containing cinnamic acid compounds have potential activity against certain drug-resistant bacteria (such as MRSA) and viruses (such as HIV protease inhibitors).
Research on biological activity
Antioxidant effects and anti-inflammatory effects. Fluorine can affect the signaling pathways of inflammation and regulate interactions between enzymes and molecules (such as COX-2).
Neuroprotectant: 4-Fluorocinnamic Acid can be used to develop drugs against Alzheimer’s or Parkinson’s diseases.
2. Materials Science
1) Organic optoelectronic material
OLED (organic-light-emitting-diode): 4-Fluorocinnamic Acid is used to increase the efficiency of devices by adding it as part of the electron-transport layer (ETL) and the light-emitting layers (EML).
Fluorine-containing liquid crystal materials: Fluorine can be used to enhance the polarity and adjust the phase transition temperatures of liquid crystals. This is ideal for display technology.
Two types of polymer materials
Photocurable resins are monomers that can be used to create UV-curable coatings and 3D printing photosensitive materials. They improve the mechanical resistance and weather resistance of materials.
Special polymers are used to prepare high-performance engineering materials such as corrosion-resistant and high-temperature-resistant plastics.
3. Agriculture chemistry
(1) Pesticide intermediates
Insecticides/fungicides: The introduction of fluorine atoms can enhance the lipid solubility and targeting of pesticides and improve their efficacy (such as pyrethroid derivatives).
Plant growth regulators. 4-Fluorocinnamic Acid regulates crop growth by affecting the synthesis of plant hormones, such as auxin.
(2) Antifungal agents
The 4-Fluorocinnamic Acid inhibits some plant pathogenic fungal species (such as powdery mildew and gray mold). It can be used in the development of new green pesticides.
4. Food and Cosmetics
Food preservatives
The 4-Fluorocinnamic Acid inhibits some foodborne pathogens, such as Escherichia coli or Salmonella. However, its application must be in compliance with food safety regulations.
Cosmetic additives
Sunscreens can absorb UVB (280-320nm) using their derivatives, such as esters.
Antioxidants: They can be found in products that are anti-wrinkle, or whiten the skin.
5. Research and other Applications
Organic Synthetic Building Blocks
It is used in the construction of complex fluorine molecules (such natural products and drug lead compounds). The double bonds and carboxyl group can be subjected to a wide range of reactions.
Two fluorescent probes and biomarkers
It can be modified to become a fluorescent detector.
The 4-Fluorocinnamic Acid can be used to detect environmental pollutants (such as heavy-metal ions or organic pollutants) and for biological imaging.
Surface modifiers
Modifying nanomaterials and metal surfaces can enhance the materials’ wettability, resistance to corrosion, or biocompatibility.
Related References
As a company specializing in the production and supply of 4-Fluorocinnamic Acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the 4-Fluorocinnamic Acid raw materials you need to support your production and research and development.
We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.
Manufacturer of 4-Fluorocinnamic Acid
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 4-Fluorocinnamic Acid manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





