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Manufacturer 4-Methylanisole CAS 104-93-8

  • Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
  • Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
  • Min: 10 Gram
  • Delivery: 7 Days
  • Transporta: Ocean, Land,Air, DHL,TNT
  • Port: Shanghai Port, Qingdao Port

Name: 4-Methylanisole

Cas: 104-93-8

Purity: 99%

MOQ: 1KG

Basic Info

p-Methyl anisole with the chemical formula C8H10O and the system name 4-Methylanisole, is a crucial fragrant ether organic substance. Structurally, it is made up of a methoxy group attached to a para methyl benzene ring using a peroxide atom. This structure incorporates the security of the benzene ring, the electron contributing effect of the methoxy team, and the weak steric limitation of the methyl team, making it unique in its physical and chemical residential or commercial properties. At space temperature level, it is an anemic and transparent liquid with a mild fragrant odor comparable to fennel. It has a high boiling point and is tough to dissolve in water, yet is quickly soluble in common organic solvents such as ethanol and ether. As a common fragrant ether, its chemical residential or commercial properties are normally much more steady than fatty ethers, however due to the solid electron donating residential property of the methoxy team, its benzene ring (particularly the ortho position of the methoxy team) is extra vulnerable to electrophilic replacement reactions, which is the basis for its participation in lots of chemical reactions.
 
The synthesis and beginning of 4-Methylanisole demonstrate its bridging duty in natural chemistry. In lab and commercial manufacturing, it is generally prepared by 2 classic techniques: one is the Williamson ether synthesis reaction between p-cresol (4-methylphenol) and methylation reagents such as dimethyl sulfate or iodomethane under alkaline problems, which is an universal technique for manufacturing asymmetric ethers; The second is acquired indirectly with paths such as Friedel Crafts alkylation or methoxylation of the benzene ring. In nature, it exists in trace amounts in specific plant essential oils, yet commercial items mostly rely on chemical synthesis. As an etherified by-product of cresol, 4-Methylanisole smartly conceals the activity of phenolic hydroxyl groups, converting them into more secure ether bonds while keeping the sensitivity of fragrant rings. This particular makes it an extremely useful precursor or intermediate in natural synthesis, often used as a safety group or a “springboard” for presenting details functional groups.

Product Introduction

Melting point -32°C
Boiling point 174 °C(lit.)
density 0.969 g/mL at 25 °C(lit.)
vapor pressure 5.25 mm Hg ( 50 °C)
refractive index n20/D 1.511(lit.)
FEMA 2681 | P-METHYLANISOLE
Fp 128 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Soluble), Ethyl Acetate (Slightly)
form Liquid
color Clear colorless to slightly yellow
Odorat 1.00 % in dipropylene glycol. naphthyl cresol ylang powdery nutty
Odor Threshold0.0012ppm
Odor Typenaphthyl
biological sourcesynthetic
explosive limit1.1-8.3%(V)
Water Solubility slightly soluble

Product Packaging

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4-Methylanisole has developed from a straightforward aromatic ether with steady ether bonds, solid electron contributing methoxy teams, and derivatizable benzene rings to a vital compound that extends several commercial chains, consisting of daily-use chemicals, premium great chemicals, life sciences, and specialized chemicals. 4-Methylanisole supplies substrate assistance in spices, acts as an adaptable and functional “molecular foundation” in synthetic chemistry, constructs core skeletons in the field of drugs and pesticides, and functions as a dependable medium in particular procedures. Its core value hinges on the fact that it is not a final product, however a platform type intermediate with high reactivity and conversion possibility. Via a collection of chain reactions, the value of fundamental chemical basic materials is enhanced layer by layer, and inevitably incorporated into numerous final result, totally mirroring the vital supporting duty of fundamental chemicals in modern-day industrial systems.

4-Methylanisole is a timeless artificial flavor monomer in the flavor market, primarily used as a fixative and modifier. It produces a light and sweet fragrance similar to fennel and ylang ylang, although not as unique as flower or fruity aromas, it has outstanding stability and persistence. It can efficiently blend various volatile elements in essence, make the total aroma extra mellow and soft, and extend the scent retention time. In addition to fragrance, 4-Methylanisole is also commonly utilized in flavor of everyday chemical items such as soaps, detergents, cosmetics, etc. Due to its stable chemical homes, it is hard to break down in acid-base media, and its cost is fairly low, it is a vital component of building the fragrance skeletal system of prominent daily needs.

In the field of organic synthesis, 4-Methylanisole is a vital multifunctional intermediate and safety precursor. Its methoxy group is a solid electron giving away team that can strongly trigger the benzene ring, especially its ortho and para placements, making it extremely susceptible to electrophilic replacement responses such as nitration, halogenation, acylation, etc, thus successfully presenting other useful teams for the synthesis of more intricate fine chemicals. At the same time, it can be restored to p-cresol in high return with demethylation responses (such as using hydroiodic acid or boron tribromide), which is usually utilized as a protective approach for phenolic hydroxyl groups in the synthesis of complex particles (such as medications and all-natural products). In addition, it is additionally an important beginning product for the synthesis of dyes, fluid crystal materials, photoinitiators, and other practical products.

4-Methylanisole plays a vital duty as a foundation in the research study and manufacturing of pharmaceuticals and pesticides. The methoxy group and methyl benzene ring in its framework are common pharmacophores or structural units in several energetic molecules. By executing a collection of derivatization reactions on the benzene ring (such as decrease to an amino group after nitration or additional functional team conversion after chlorination), diverse intermediates can be created for the synthesis of drugs such as nonsteroidal anti-inflammatory medications, prescription antibiotics, cardio medicines, and so on. In chemical chemistry, it is additionally an essential aromatic fragment for synthesizing specific pesticides and herbicides, and its metabolic security helps to lengthen the effectiveness. The structural variety supplied by it as a forerunner is a crucial chemical basis for discovering and maximizing new energetic substances.

4-Methylanisole is made use of as an unique high boiling point natural solvent due to its high boiling point (roughly 174 ° C), modest polarity, good solubility, and chemical inertness. It is particularly ideal for chemical reactions that call for high temperatures and are sensitive to proton solvents, such as some Friedel Crafts responses, Grignard reagent reactions, or as solvents for recrystallization. In the electronics industry and materials scientific research, it is also made use of to dissolve and process certain resins or as a part of cleansing agents. Although its solvent application is not as considerable as toluene and xylene, it is a reliable selection in details situations where the security and fragrant solubility of ether solvents are needed.

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Manufacturer of 4-Methylanisole

Company Info

Zhishang chemical company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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Raymond
I would like to thank Shandong Zhishang New Materials Co., Ltd. for a very efficient transaction with their team.
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Raymond Louis
The goods have been delivered intact. good packing. honest seller
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As usual, a great service from dear zhishang chemical, and the perfect quality of product! Highly recommend this company, and hope for long and productive cooperation :)
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We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

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Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

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