Name: 4-Methylthiazole
Cas: 693-95-8
Purity: 99%
MOQ: 1KG
Directory Guidance on 4-Methylthiazole
Nature and Specifications
| MF: | C4H5NS |
| MW: | 99.15 |
| EINECS: | 211-764-1 |
Basic Info
4-Methylthiazole, also known as 4-Methylthiazole in English, is a transparent colorless to light yellow liquid at room temperature and pressure, and is insoluble in water. 4-Methylthiazole is a thiazole derivative, which contains a sulfur and a nitrogen five-membered ring in its structure. It can be used as an organic synthesis reagent to participate in various coupling reactions catalyzed by palladium, and is mainly used in the synthesis of drugs, dyes, rubber accelerators, film coloring, fungicides and dyes. In addition, 4-methylthiazole has a certain nutty aroma and is a food flavoring.
4-Methylthiazole contains a sulfur and a nitrogen five-membered ring in its structure and is weakly alkaline. The carbon-hydrogen bond at the 5th position of this substance has high chemical reactivity, and it can undergo cross-coupling reaction with aromatic halides under the action of metal catalyst palladium. The thiazole ring in the structure of this substance is a very important five-membered aromatic heterocycle, which has abundant electrons and is easy to form hydrogen bonds, coordinate with metal ions, and interact with various non-covalent bonds such as stacking, electrostatics and hydrophobic effects. Since both the sulfur atom and the nitrogen atom contain a lone pair of electrons, the substance is sensitive to oxidants, and direct contact with oxidants can easily lead to the destruction of the thiazole ring.
Product Introduction
| Melting point | 134 °C |
| Boiling point | 133-134 °C (lit.) |
| density | 1.09 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.524(lit.) |
| FEMA | 3716 | 4-METHYLTHIAZOLE |
| Fp | 90 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | Liquid |
| pka | pK1:3.16(+1) (25°C,μ=0.1) |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.090 |
| Odor | at 0.10 % in dipropylene glycol. nutty green vegetable tomato |
| Odor Type | nutty |
⇒We provide high-purity chemical raw materials with clear molecular formula and precise specifications. Each batch of 4-Methylthiazole products undergoes strict quality inspection to ensure stable and reliable physical and chemical properties. It adopts international standard packaging, sealed and moisture-proof, to ensure safe transportation and storage. Whether it is R&D experiments or industrial production, we can provide you with professional technical support and customized services. With rigorous technology, transparent data and stable supply, we help you efficiently complete chemical applications and innovations.

Chemical Industry
4-Methylthiazole is mainly used as an organic synthesis intermediate in the chemical industry to prepare a variety of fine chemicals. The thiazole ring in its molecular structure has good reactivity and can generate various derivatives through substitution, condensation and other reactions. For example, in the synthesis of nitrogen-containing heterocyclic compounds, it can be used as a key intermediate to participate in the preparation process of drugs, pesticides and functional materials, providing a structural basis for the construction of complex molecules.
Pharmaceutical Industry
In the pharmaceutical industry, derivatives of 4-methylthiazole are often used to develop biologically active drug molecules. The biocompatibility of the thiazole ring and its ability to bind to the target make it an important structural unit in drug design. For example, the synthesis of some antibacterial and antiviral drugs uses 4-methylthiazole as a starting material, and its substituents are modified to enhance the affinity of the drug with the target enzyme and improve the efficacy.
Pesticide Industry
4-Methylthiazole can be used as an active ingredient or intermediate of insecticides and fungicides in the preparation of pesticides. The sulfur and nitrogen atoms in its structure give the compound a certain biological toxicity, which can act on the nervous system of insects or the metabolic pathways of fungi, thereby achieving the effect of preventing and controlling pests and diseases. For example, some insecticides containing 4-methylthiazole structure can inhibit the activity of insect acetylcholinesterase, resulting in the blockage of pest nerve conduction and death; in fungicides, this structure can interfere with the respiration or cell wall synthesis of fungal cells, prevent the reproduction of pathogens, and is often used for the prevention and control of diseases of fruits, vegetables and crops.
Flavors and Food Additives
4-methylthiazole has unique olfactory characteristics and can be used as a blending ingredient for edible flavors or daily flavors in the flavor industry. Its aroma is often described as having a roasted nut, meat or burnt aroma, which can add a rich flavor to foods (such as baked goods and meat products), and can also be used in the blending of seasonings to enhance the taste level.
Materials and Coatings
In the field of functional materials, 4-methylthiazole can be used as a ligand or functional monomer to participate in material preparation. For example, in metal anti-corrosion coatings, its derivatives can form coordination bonds with the metal surface to build a dense protective film and inhibit electrochemical corrosion; in optoelectronic materials, conjugated polymers containing thiazole structures can be used as light-emitting layer or conductive layer materials in organic light-emitting diodes (OLEDs) or sensors, and the electronic transmission characteristics of their molecular structures can be used to improve device performance.
Analytical Chemistry and Reagents
4-Methylthiazole can be used as a standard reagent or analytical aid in analytical chemistry. For example, in gas chromatography (GC) or liquid chromatography (HPLC) analysis, it can be used as a qualitative or quantitative reference to calibrate instruments or verify the accuracy of methods; in the monitoring of organic synthesis reactions, the stability of its structure and characteristic spectra (such as infrared and nuclear magnetic resonance) can help researchers track the progress of reactions.
Welcome to Consult
If you are looking for high-quality 4-Methylthiazole, now is the best time! We not only provide you with very competitive prices, but also strictly guarantee the purity and stability of the products to the industry-leading level. At the same time, our comprehensive after-sales service will accompany you every step from procurement to use to protect your business.
Choose us, you will experience:
Excellent quality: products meet international standards, stability and purity are verified multiple times.
Professional service: quick response to needs, provide detailed technical support.
Long-term trust: we are committed to building lasting partnerships to help your business grow.
Related References
Manufacturer of 4-Methylthiazole
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 4-Methylthiazole manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.






