Name: 5-(2-Hydroxyethyl)-4-Methylthiazole
Cas: 137-00-8
Purity: 99%
MOQ: 1KG
Directory Guidance on 5-(2-Hydroxyethyl)-4-Methylthiazole
Chemical Structure

Basic Info
5-(2-Hydroxyethyl)-4-Methylthiazole is an important organic compound belonging to the thiazole class derivatives, with a special sulfur-containing five-membered heterocyclic structure. It is often used as an important precursor for synthesising biomolecules such as vitamin B1 (thiamine) in chemical raw materials. Due to its unique sulfur atom and hydroxyl structure, 5-(2-Hydroxyethyl)-4-Methylthiazole exhibits specific activity in biological and chemical reactions and is commonly used in biosynthesis and pharmaceutical intermediates. In addition, this compound is an ideal choice for synthesising vitamin products due to its stability and effectiveness.
Product Introduction
| Melting point | <25 °C |
| Boiling point | 135 °C7 mm Hg(lit.) |
| density | 1.196 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.550(lit.) |
| FEMA | 3204 | 4-METHYL-5-THIAZOLEETHANOL |
| Fp | >230 °F |
| storage temp. | 2-8°C |
| solubility | alcohol: soluble(lit.) |
| form | liquid (clear, viscous) |
| pka | 14.58±0.10(Predicted) |
| color | deep yellow |
| Specific Gravity | 1.196 |
| Odor | meaty, roasted odor |
| Odor Type | meaty |
| MF: | C6H9NOS |
| MW: | 143.21 |
| EINECS: | 205-272-6 |
| Item | Specification |
| Product Name | 5-(2-Hydroxyethyl)-4-Methylthiazole |
| CAS No. | 137-00-8 |
| Appearance | liquid |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Pharmaceutical field
The synthesis of vitamin B1: 5- (2-Hydroxyethyl) -4-methylthiazole is a key intermediate for synthesising vitamin B1 (thiamine). Vitamin B1 is crucial for the human nervous, cardiovascular, and glucose metabolism. As a water-soluble vitamin, it is commonly used to treat vitamin B1 deficiency, help alleviate fatigue, improve memory, prevent and treat beriberi, etc. The use of 4-methyl-5-hydroxyethyl thiazole ensures the purity and stability of vitamin B1, making it a key ingredient in many health products and pharmaceuticals.
Intermediate for drug synthesis: Due to its structural activity, 5- (2-Hydroxyethyl) -4-methylthiazole has also been used to synthesize other thiazole drugs. Thiazole compounds have various pharmacological activities, including antibacterial, antiviral, and anti-tumour properties, providing a foundation for developing innovative drugs.
2. Food additives
The production of nutritional fortifiers 5- (2-Hydroxyethyl) -4-methylthiazole indirectly supports the production of nutritional fortifiers. Vitamin B1, as an important nutritional additive, is widely used in fortified foods such as bread, grains, beverages, and infant formula. By efficiently synthesising this raw material, the production of vitamin B1 has been increased, ensuring the nutritional supplementation of food products and meeting the growing demand for nutritional fortifiers.
Flavour preparation: in some foods, 5- (2-Hydroxyethyl) -4-Methylthiazole can give a yeast-like light aroma, improve food flavour, and make it suitable for the essence and spice industry. For example, it can be used in certain seasonings, meat products, and sauces to enhance the flavour of ingredients and make products more attractive.
3. Biochemical research
Biosynthesis pathway simulation: 5- (2-Hydroxyethyl) -4-methylthiazole plays an important role in simulating metabolic pathways in organisms. Its unique structure and reactivity make it an ideal choice for researchers to simulate the biosynthesis pathway of vitamin B1 in vitro experiments. Scientists can understand the synthesis mechanism, metabolic pathways, and related enzyme reactions of vitamin B1 by studying the behaviour of this compound, which has profound significance for basic research in biochemistry and molecular biology.
Research on enzyme reactions: Under in vitro conditions, 5- (2-Hydroxyethyl) -4-methylthiazole can simulate certain enzyme-catalyzed reactions, providing a reference for enzyme engineering and developing new catalysts. Especially for enzyme reactions involving thiazole structures, this raw material can provide an important experimental basis for research.
4. Spices and essence
Unique aroma characteristics: 5- (2-Hydroxyethyl) -4-methylthiazole can produce unique yeast and wheat aromas, making it of special value in fragrance formulations. It can blend essence and spices, especially to increase the flavour depth and simulate the natural flavour. For example, in some sauces, meats, and snack products, the fragrance they produce is used to enhance the flavour level of the product and improve the user experience.
Applied in spice production: These thiazole compounds are often used to blend more advanced compound spices in the spice industry. 5- (2-Hydroxyethyl) -4-methylthiazole can enhance the aroma of food at low concentrations, giving it a natural flavour. Due to its good thermal stability and ability to maintain its aroma characteristics during high-temperature processing, it is widely used in baking and high-temperature processed foods.
5. Potential applications in the cosmetics industry
Due to the increasing research on the application of thiazole compounds in cosmetics, 5- (2-Hydroxyethyl) -4-methylthiazole may be explored for use in developing cosmetic raw materials in the future. Its unique structure and activity may provide stability in certain skincare ingredients or offer additional benefits as an antioxidant.
Related References
Manufacturer of 5-(2-Hydroxyethyl)-4-Methylthiazole
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional 5-(2-Hydroxyethyl)-4-Methylthiazole manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





