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Acetophenone cas 202-708-7
If you have ever caught a faint almond-and-jasmine note drifting from a scented candle, a fragrance base, or even a flavoring compound in your kitchen cupboard, there is a decent chance acetophenone had something to do with it. As a supplier working with this compound daily — from raw material intake to drummed export shipments — we get the same questions over and over from buyers in cosmetics, flavor houses, and specialty chemical manufacturing. This article pulls those questions together, along with a look at how the material is actually made, what separates a reliable factory from an unreliable one, and what to expect when it comes to packaging and logistics
Name: Acetophenone
Cas: 98-86-2
Purity: 99%
MOQ: 1KG
Basic Info
Acetophenone (chemical formula C₆H₅COCH₃, CAS No. 98-86-2) is an aromatic ketone that occurs as a colorless to pale-yellow liquid with a sweet, slightly floral, almond-like odor. It’s one of those “workhorse” intermediates that shows up across several industries at once:
- Cosmetics and fragrance — used as a fragrance fixative and aroma component in perfumes, soaps, detergents, and scented personal care products because of its pleasant, long-lasting scent profile.
- Flavor and food-adjacent applications — acts as a flavoring agent in trace concentrations, contributing to fruity or nutty notes in certain formulations.
- Pharmaceutical intermediates — serves as a building block in the synthesis of various active pharmaceutical ingredients and specialty chemicals.
- Resins and polymers — used in the production of certain resins, and as a polymerization catalyst or photoinitiator precursor in UV-curable systems.
- Solvent applications — occasionally used as a solvent for cellulose acetate, nitrocellulose, and various plastics.
Physically, it has a melting point around 20°C, a boiling point near 202°C, and is only slightly soluble in water but miscible with most organic solvents — properties that matter quite a lot when you’re designing a formulation around it or figuring out how to store and transport it safely.
Application
How Acetophenone Is Manufactured
There isn’t just one route to acetophenone, and the production method a supplier uses tends to say a lot about the purity grade, consistency, and cost structure you’ll end up with.
1. Co-product of cumene/ethylbenzene oxidation processes A large share of commercial acetophenone is recovered as a byproduct of ethylbenzene oxidation during styrene monomer production. In this route, ethylbenzene is oxidized to ethylbenzene hydroperoxide, which is then processed further; acetophenone forms as a secondary product and is separated out through fractional distillation. This method tends to produce large volumes at competitive cost, though the purity depends heavily on how tightly the downstream distillation is controlled.
2. Friedel-Crafts acylation of benzene Acetophenone can be synthesized directly by reacting benzene with acetyl chloride or acetic anhydride in the presence of a Lewis acid catalyst such as aluminum chloride. This route gives more direct control over purity but is generally more costly at scale and is more common for specialty or high-purity fragrance-grade material.
3. Catalytic dehydrogenation of 1-phenylethanol (sec-phenylethyl alcohol) This oxidation route converts 1-phenylethanol into acetophenone using a metal catalyst under controlled temperature. It’s often favored when the target is a cleaner ketone profile with fewer aromatic byproducts, which matters for fragrance and cosmetic-grade applications where trace impurities can affect scent.
For cosmetic and fragrance applications specifically, the finishing steps matter as much as the core reaction — vacuum distillation, activated carbon treatment, and moisture control all play a role in bringing a technical-grade output up to a fragrance- or cosmetic-acceptable purity, typically 99% or higher with tightly controlled color (APHA) values.
Our Factory
Buyers sourcing acetophenone for cosmetic or fragrance use are rarely just buying a chemical formula — they’re buying consistency, batch-to-batch reproducibility, and documentation they can hand to their own regulatory or QC teams. A handful of practical factors tend to separate factories worth working with from ones that cause headaches down the line:
- In-house distillation and purification control, rather than relying entirely on outsourced refining, which reduces variability between batches.
- Batch-level COA (Certificate of Analysis) issued for every shipment, covering purity, color (APHA/Hazen), moisture content, and acid value.
- Stable raw material sourcing, since acetophenone quality is only as good as the ethylbenzene, benzene, or phenylethanol feedstock going into it.
- Odor and color consistency testing before release — a subtle shift in scent profile can be a dealbreaker for a fragrance house even if the assay purity looks fine on paper.
- Regulatory documentation support — SDS sheets, REACH registration status, IFRA compliance notes for fragrance use, and country-specific import documentation.
- Responsive technical support for buyers who need guidance on solubility, blending behavior, or storage stability in their specific formulation.
A factory that can walk a new customer through all of the above without hesitation, and that’s willing to send pre-shipment samples for independent verification, is usually one worth building a longer-term relationship with.
Product Packaging
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One thing that trips up a lot of first-time buyers is assuming that “available on Alibaba” equals “available in the tonnage you need, on the timeline you need.” Production capacity varies enormously between suppliers — some are essentially repackaging traders, others run dedicated reactor and distillation lines.
When evaluating a supplier’s capacity, it’s worth asking directly about:
- Annual production tonnage and how much of that is allocated to export versus domestic sale
- Minimum order quantity (MOQ), which can range from a single 200kg drum for trial orders up to full ISO-tank or flexitank quantities for bulk buyers
- Lead time for standard grade versus custom-purity or custom-packaged orders
- Buffer stock levels, since acetophenone demand can spike seasonally in fragrance manufacturing ahead of major product launches
A factory running continuous or semi-continuous distillation trains, rather than batch-only processing, will generally offer more reliable lead times and tighter purity tolerances across large orders.
Related References
FAQ
FAQ
Q1: What should be done if Acetophenone solidifies during cold-weather transit? A: Solidification below 19.5°C is a natural physical characteristic of pure Acetophenone (CAS 98-86-2) and does not affect product quality. Gently warm the sealed drum or container in a warm room or indirect warm water bath (30°C–40°C) until fully liquefied, then mix thoroughly before sampling or use.
Q2: How does the purity level of 99.5% benefit pharmaceutical synthesis compared to technical grades? A: A minimum purity of 99.5% with strictly controlled moisture and low free acid levels minimizes unreacted impurities during organic synthesis. This leads to higher reaction yields, fewer side products, and easier downstream crystallization processes.
Q3: Is Acetophenone compatible with strong oxidizing or reducing agents? A: As an aromatic ketone, Acetophenone can react vigorously with strong oxidizing agents, strong bases, and reducing agents. It should be stored in isolated, well-ventilated areas away from direct heat, open flames, and incompatible chemical materials.
Q4: What standard packaging options are available for industrial bulk orders? A: Standard packaging includes 200 kg steel drums, 1000 kg IBC totes, or ISO tank containers for high-volume orders. All containers are sealed under moisture-resistant conditions to preserve product purity during long-distance maritime transport.
Cooperation Partner
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