High-Purity Calcium Thioglycolate CAS 814-71-1 | Manufacturer & Supplier - Zhishang Chem
Name: Calcium Thioglycolate
Cas: 814-71-1
Purity: 99%
MOQ: 1KG
Directory Guidance on Calcium Thioglycolate
Chemical Structure

Basic Info
| storage temp. | 2-8°C, sealed storage, away from moisture |
| Appearance | White to off-white Solid |
| Water Solubility | soluble H2O [MER06] |
| Merck | 1711 |
| Cosmetics Ingredients Functions | KERATOLYTIC REDUCING DEPILATORY |
| Cosmetic Ingredient Review (CIR) | Calcium thioglycolate (814-71-1) |
| InChI | InChI=1S/2C2H4O2S.Ca/c2*3-2(4)1-5;/h2*5H,1H2,(H,3,4);/q;;+2/p-2 |
| InChIKey | CNYFJCCVJNARLE-UHFFFAOYSA-L |
| SMILES | [Ca+2].C([O-])(=O)CS.C([O-])(=O)CS |
| LogP | 0.089 (est) |
To facilitate seamless international trade and uphold complete compliance for global cosmetics and industrial chemical supply chains, Shandong Zhishang Chem operates within robust quality management systems:
ISO 9001:2015 Certification: Standardized manufacturing workflows and strict quality assurance from raw precursor intake to finished goods packaging.
EU REACH Regulatory Alignment: Pre-registered documentation and full inventory status support for seamless distribution across European markets.
Batch Traceability & Documentation: Every commercial shipment is dispatched with an authentic Certificate of Analysis (COA) and an updated Safety Data Sheet (SDS).
Cosmetic Safety Standards: Verified ultra-low residual trace metals (Lead ≤ 10 ppm, Arsenic ≤ 2 ppm, Iron ≤ 20 ppm) and stringent microbiological controls ensuring safety in topical applications.
Product Packaging
Quality verification at Zhishang Chem operates under a three-stage self-inspection protocol within our standardized laboratory system before any product leaves the facility:
Raw Material Precursor Screening: Quantitative titrimetric and chromatographic evaluation of raw thioglycolic acid and calcium precursors to eliminate heavy metal traces at the source.
In-Process Reaction Monitoring: Real-time tracking of crystallization pH, temperature gradients, and stoichiometric stoichiometry to guarantee correct hydration state (trihydrate form) and minimize unreacted organic acid levels.
Analytical Batch Release Testing: Final verification through iodine titration and Atomic Absorption Spectroscopy (AAS) ensures exact thioglycolate content, bulk density uniformity, and compliance with heavy metal limits.
A. Cosmetic Depilatory Formulations
In personal care engineering, Calcium Thioglycolate serves as a core active ingredient in professional hair removal creams, lotions, and gels. Its functional mechanism involves the selective cleavage of disulfide bonds (R-S-S-R) within keratin proteins, softening the hair shaft structure for swift and painless removal at skin level. Compared to sodium or potassium hydroxides, Calcium Thioglycolate provides a controlled, mild alkaline reaction, rendering it highly suitable for sensitive skin applications.
B. Polymer & PVC Heat Stabilization
In thermoplastic processing, Calcium Thioglycolate acts as a highly efficient co-stabilizer in both rigid and flexible polyvinyl chloride (PVC) compounds. By scavenging labile chlorine atoms along the polymer chain and neutralizing liberated hydrogen chloride (HCl) during thermal extrusion, it effectively inhibits thermal degradation, prevents yellowing, and maintains structural toughness.
FAQ
A: Calcium Thioglycolate exhibits lower solubility kinetics and a milder alkaline release compared to alkali metal salts. This offers a more controlled depilatory reaction, substantially reducing skin irritation risks while maintaining high efficacy in sensitive personal care formulas.
A: Yes, we offer complimentary evaluation sample packages (100g to 500g) along with lot-specific COAs for laboratory testing. For commercial orders, we provide standard 25 kg fiber drums as well as custom moisture-proof bag packaging according to customer specifications
Related References
Pubchem-Calcium Thioglycolate
Chemicalbook-Calcium Thioglycolate
Manufacturer of Calcium Thioglycolate
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.






