Name: Dexamethasone Sodium Phosphate
Cas: 55203-24-2
Purity: 99%
MOQ: 1KG
Directory Guidance on Dexamethasone Sodium Phosphate
Chemical Structure
Basic Info
Dexamethasone sodium phosphate is a synthetic glucocorticoid drug with the chemical name of 16a-methyl-11b,17a,21-trihydroxy-9a-fluoropregnane-1,4-diene-3,20-dione-21-phosphate disodium salt. Its molecular mass is 516.41 and its formula is C22H28FNa2O8P. Dexamethasone sodium is a phosphate derivate that has a high water solubility. It can be easily made into eye drops or injections. Its chemical composition contains fluorine, which increases its anti-inflammatory effects and immunosuppressive properties.
Dexamethasone sodium is made by phosphating the dexamethasone. This chemical modification improves not only the solubility, but also the bioavailability of the drug. Dexamethasone Sodium Phosphate is used as a raw materials in the pharmaceutical industry for anti-inflammatory, immunosuppression, and anti-allergic purposes. Although its chemical properties are stable under normal conditions, it can degrade when exposed to light or high temperatures. It is therefore best stored in a dry and cool place.
Product Introduction
| Melting point | 204-206°C (dec.) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, faintly yellow |
| form | Solid |
| color | white to off-white |
| MF: | C22H28FNa2O8P |
| MW: | 516.4 |
| EINECS: | 219-243-0 |
| Item | Specification |
| Product Name | Dexamethasone Sodium Phosphate |
| CAS No. | 55203-24-2 |
| Appearance | liquid |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Anti-inflammatory treatment
Dexamethasone is an anti-inflammatory drug that has been widely used in the treatment of various inflammatory conditions. As an example:
Rheumatic disease: such as ankylosing-spondylitis and rheumatoid, these diseases reduce swelling of the joints by blocking the release inflammatory mediators.
Respiratory diseases, such as asthma and chronic obstructive lung disease (COPD), are treated to reduce acute attacks and chronic inflammation.
Dermatological diseases, such as eczema and dermatitis (psoriasis), can be treated with topical or injectable medications to reduce the skin inflammation.
Mechanism of Action: By inhibiting phospholipase-A2, it reduces the production of mediators of inflammation such as leukotrienes and prostaglandins.
2. Anti-allergic treatment
Clinical application: Used to treat allergic diseases such as:
Allergic rhinitis : relief of symptoms such as nasal congestion and runny nose.
Reduce skin redness and itchiness.
Anaphylactic shock is a drug that can be used as an emergency to relieve severe allergic reactions.
The mechanism of action is to reduce the severity of allergic reactions through the inhibition of the activation and release of histamine by immune cells.
3. Immunosuppression
Use in treating autoimmune diseases such as:
SLE: Suppresses the immune system from attacking its own tissues.
Prevents transplantation rejection and is often combined with other immunosuppressive drugs.
Mechanism of action: Inhibits proliferation of B and T lymphocytes, which reduces the activity of immune cells.
4. First aid and critical Care
Clinical application: It has a major role in emergency medicine.
Shock treatment: It improves the microcirculation, especially for anaphylactic and septic shocks. This is done by stabilizing the cell membranes and decreasing the release of inflammation mediators.
Cerebral Edema: Reduces intracranial pressure, and helps relieve cerebral edema due to brain tumors or brain trauma.
Benefits: Dexamethasone phosphate sodium is water soluble and can be made as injections. It is a first-aid treatment that has a rapid effect.
5. Tumor Support Treatment
Clinical application: can be used as an adjunct in the treatment of tumors, for instance.
As an antiemetic it can reduce side effects from chemotherapy.
Anti-inflammatory properties relieve symptoms of tumor-related edema, such as those caused by brain tumours or spinal cord compresssion.
Mechanism of action: inhibits the vomiting reflex and reduces inflammatory reactions.
6. Ophthalmic Application
Clinical application: widely used to treat ophthalmic conditions, such as:
Postoperative anti-inflammatory : used to control inflammation after ophthalmic surgeries such as cataracts or glaucoma.
Ocular inflammation: such a keratitis or uveitis. Topically administered eye drops and eye ointments.
Advantages: The dexamethasone phosphate sodium has a good water solubility, making it suitable for eye drops. It also has fewer side-effects when applied topically.
7. Veterinarian field
Also widely used in the veterinary sector, for example.
Inflammatory diseases of animals: arthritis, dermatitis etc.
Animal allergy diseases include allergic skin diseases, allergic respiratory diseases and allergic skin diseases.
Benefits: Fast onset, significant efficacy. Commonly used to treat pets and livestock.
8. Pharmaceutical preparations
Dexamethasone Sodium Phosphate is a chemical API that can be used in a number of preparation forms.
Injections: used in emergency and critical care.
Eye drops are used to treat ophthalmic conditions locally.
External preparations, such as creams or ointments are used to treat skin conditions.
Chemical properties: high stability and good solubility in water. Suitable for various preparation processes.
Related References
As a company specializing in the production and supply of Dexamethasone Sodium Phosphate raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required Dexamethasone Sodium Phosphate raw materials to support your production and research and development.
We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.
Manufacturer of Dexamethasone Sodium Phosphate
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Dexamethasone Sodium Phosphate manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
