Heptaethylene glycol monododecyl ether (CAS 3055-97-8) | High Purity C12E7 Non-Ionic Surfactant Manufacturer
Name: Heptaethylene Glycol Monododecyl Ether
Cas: 3055-97-8
Purity: 99%
MOQ: 1KG
Directory Guidance on Heptaethylene Glycol Monododecyl Ether
Chemical Structure

Basic Info
Heptaethylene glycol monododecyl ether (CAS 3055-97-8): Defined Hydrophile C12E7 Non-Ionic Surfactant for Specialized Applications
Heptaethylene glycol monododecyl ether (commonly designated as C12E7) is a well-defined monodisperse non-ionic surfactant belonging to the polyoxyethylene alkyl ether family. Consisting of a uniform dodecyl (C12) hydrophobic tail attached to a hydrophilic chain of seven ethylene oxide units, this compound exhibits precise amphiphilic balances and well-characterized self-assembly behaviors in aqueous media.
Unlike polydisperse commercial laureth mixtures, high-grade C12E7 offers exceptionally consistent critical micelle concentration (CMC) and aggregation properties. This high degree of molecular uniformity makes it a vital reagent in structural biology, membrane protein extraction, surface chemistry research, and high-end industrial emulsification.
| Melting point | 27-29 °C |
| Boiling point | 553.9±45.0 °C(Predicted) |
| density | 0.977~0.983g/ml (35℃) |
| refractive index | 1.448~1.454 (35℃/D) |
| Fp | 27 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | 14.36±0.10(Predicted) |
| color | Colourless |
| Cosmetics Ingredients Functions | SURFACTANT – EMULSIFYING SURFACTANT – CLEANSING |
To guarantee reliable performance across sensitive scientific assays and commercial manufacturing, our production and distribution pipelines adhere to global industry standards.
ISO 9001:2015 Certification: Full implementation of quality control systems across manufacturing, handling, and batch packaging phases.
ISO 14001:2015 Environmental Management: Standardized chemical waste reduction and safe handling parameters during synthesis.
REACH Registration Compliance: Documentation and tonnage compliance for seamless import and distribution within EU markets.
Regulatory Dossier Availability: Complete safety and technical packages are accessible, including GHS-compliant Safety Data Sheets (SDS), Certificates of Analysis (COA) per batch, and Origin & Composition Statements.
Product Packaging
To prevent batch-to-batch variance that could disrupt sensitive research or formulation stability, every production lot of CAS 3055-97-8 undergoes rigid in-house analytical verification:
Purity & Oligomer Distribution Analysis (HPLC-ELSD / GC-MS): Chromatographic profiling is performed to verify the narrow distribution of the C12 tail and exact C7 ethoxy length, ensuring active content exceeds required specifications.
Water Content & Moisture Determination (Karl Fischer Titration): Strict moisture limits are verified to ensure stability during storage and accurate solution preparation.
Cloud Point Determination: Measured in aqueous solutions to verify phase separation thresholds, ensuring consistent thermal stability in downstream processing.
Free Ethylene Oxide & Dioxane Residual Testing: Trace analysis via head-space gas chromatography (HS-GC) ensures residual impurity levels remain safely below global regulatory thresholds.
Peroxide Value Assessment: Colorimetric assays monitor potential oxidative degradation products, preserving sample integrity for lipid bilayer and protein-handling work.
Heptaethylene glycol monododecyl ether serves vital functions across research and industrial domains:
Membrane Protein Solubilization & Crystallization: Due to its mild non-denaturing characteristics and narrow micelle size, C12E7 is widely utilized by biochemists to extract, purify, and stabilize hydrophobic membrane proteins without altering their native conformation.
Biophysical & Surface Chemistry Research: Serves as a reliable model surfactant for studying micellization dynamics, microemulsion formation, phase diagrams, and interfacial tension lowering.
High-Performance Industrial Emulsifier: Used as a non-ionic emulsifying agent in specialty coatings, microemulsions, and specialized agrochemical formulations requiring precise hydrophilic-lipophilic balance (HLB ≈ 12.3).
Specialty Cleaning & Micro-Detergency: Acts as an effective wetting agent and low-foaming detergent in high-precision electronic component cleaning and surface treatment protocols.
FAQ
A: Commercial Laureth-7 is typically a polydisperse mixture containing a wide distribution of ethylene oxide chain lengths (e.g., EO 2 through EO 12). Defined C12E7 (CAS 3055-97-8) features a highly uniform C7 polyoxyethylene chain, providing reproducible micellar dimensions, consistent phase transition temperatures, and reliable performance in analytical or biochemical environments.
A: Yes, owing to its amphiphilic structure, C12E7 demonstrates good solubility in water at room temperature, as well as in common organic solvents such as ethanol, methanol, chloroform, and ethyl acetate.
A: Absolutely. As a non-ionic surfactant, C12E7 exhibits high electrostatic compatibility and can be readily formulated alongside anionic, cationic, or zwitterionic surfactants to adjust viscosity, foam profile, or micellar stability.
Related References
Pubchem-Heptaethylene Glycol Monododecyl Ether
Chemicalbook-Heptaethylene Glycol Monododecyl Ether
Manufacturer of Heptaethylene Glycol Monododecyl Ether
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