Name: Honokiol
Cas: 8002-09-3
Purity: 99%
MOQ: 1KG
Directory Guidance on Honokiol
Chemical Structure
Basic Info
Honokiol is one of the two active ingredients in the Chinese medicine Magnolia offficinalis. The structure of the compound is shown below. It is a diphenyl biphenyl compound with an allyl group. Honokiol has a variety of biological activities, such as antibacterial, anti-inflammatory, central muscle relaxation and nerve inhibition, antiplatelet, cholesterol-lowering, anti-tumor and other pharmacological effects. The anti-tumor effects of Honokiol have received increasing attention.
Honokiol is the active ingredient in the Chinese medicine Magnolia offficinalis. It has many biological effects including moderate anti-tumor properties. Honokiol inhibits the growth of cancerous tumors in vitro and vivo, including lung cancer, gastrointestinal tumours, head-and-neck squamous cells carcinoma, breast, prostate and ovarian tumors. It can target a variety of targets, including apoptosis related signaling, growth factor-mediated pathways, NF-kB pathways, androgen receptors. HNK can enhance the anti-tumor effects of targeted anti-tumors or traditional anti-tumors, and reverse drug resistance in tumor cells against cisplatin doxorubicin paclitaxel etc. The combination of anti-tumor drug and honokiol has the effect of increasing and reversing resistance to drugs. It is used as a biochemical regulatory in clinical practice.
Product Introduction
| Melting point | 86℃ |
| Boiling point | 400.1±40.0 °C(Predicted) |
| density | 1.107±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 36 mg/mL |
| form | powder |
| pka | 9.89±0.48(Predicted) |
| color | White to Off-White |
| MF: | C18H18O2 |
| MW: | 266.33 |
| EINECS: | 609-119-8 |
| Item | Specification |
| Product Name | Honokiol |
| CAS No. | 8002-09-3 |
| Appearance | Powder |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Medical field
Honokiol is a pharmacological agent with significant antibacterial, antiinflammatory, and antitumor activities. It’s used in the treatment of digestive system disorders such as acute gastroenteritis, bacillary diarrhoea, and chronic gastritis. It also has neuroprotective effects, can reduce thrombosis and inhibit platelet aggregation. It can also be used to treat mental disorders such as anxiety and depression. Its muscle relaxing properties also make it suitable for athlete rehabilitation and spasticity treatments.
2. Anti-tumor Research
Honokiol has been shown in studies to inhibit the growth and induce apoptosis of cancerous cells, such as glioblastoma and breast cancer. This is done by regulating signaling pathway Akt and ERK1/2. Its antiangiogenic effects can block blood supply to tumors and increase the effectiveness of chemotherapy drugs.
3. Antibacterial oral care
Honokiol is more effective than berberine at inhibiting Streptococcus Mutans (the bacteria that causes caries) and can therefore be used to make anti-caries mouthwash and toothpaste, which reduces dental plaque. It also has an inhibitory effect against Staphylococcus mutans and fungi. This makes it suitable for developing anti-infective medications.
4. Cardiovascular protection
Honokiol inhibits thrombosis and reduces myocardial damage. It can also regulate calmodulin activity (CaM), improve cardiovascular function, and even prevent heart disease. Its antioxidant properties reduce the oxidative damage to blood vessel walls and are useful for the prevention and treatment of cardiovascular and cerebral diseases.
5. Food and Health Products
While honokiol has a medical use, it is also useful in health and functional food products. Its antioxidant and anti-aging properties can delay aging or enhance immunity. It has not been widely used in food additives, and further research is needed to determine its safety.
6. Cosmetics and skin products
Honokiol’s anti-inflammatory and antioxidant qualities can be used to reduce skin inflammation, and to protect skin from free radical damage. Its antibacterial properties can also be used to control acne and oil.
7. Agriculture and Plant Protection
Honokiol’s antibacterial and antifungal properties can be used in the development of botanical pesticides to reduce chemical pesticide use and improve crop resistance. Its role in regulating the metabolism of plants may also affect crop growth. However, related research is under investigation.
Related References
If you are looking for high-quality Honokiol, now is the best time! We not only provide you with very competitive prices, but also strictly guarantee the purity and stability of our products to the industry-leading level. At the same time, our comprehensive after-sales service will accompany you every step from procurement to use to protect your business.
Choose us, you will experience:
Excellent quality: products meet international standards, stability and purity are verified multiple times.
Professional service: quick response to needs and detailed technical support.
Long-term trust: we are committed to building lasting partnerships to help your business grow.
Please contact us now for more product details and exclusive quotes. Let us become your only choice for chemical raw material procurement and open a new chapter of cooperation together!
Manufacturer of Honokiol
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Honokiol manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
