Name：L-Ergothioneine
Cas: 497-30-3
Purity: 99%
MOQ: 1KG
L-Ergothioneine is an uncommon, naturally taking place chiral amino acid derivative identified by a special, extremely secure 2-mercaptoimidazole ring linked to a trimethylated histidine deposit. This one-of-a-kind molecular framework conveys exceptional stability, making it immune to auto-oxidation under physical problems and not likely to come to be a pro-oxidant after reactions, as accompanies some anti-oxidants. Very first discovered in ergot fungis in 1909, it is located in a wide variety of microorganisms, from microbes and fungis to the animal kingdom. Nevertheless, it is noteworthy that a lot of plants and mammals can not synthesize it themselves and need to rely upon nutritional consumption or specialized biosynthetic paths for its manufacturing.
Biochemically, L-Ergothioneine is known as the “master antioxidant” and the “utmost guardian of the cell.” Its very high focus in mitochondria underscores its central role in securing the cellular power source from oxidative damages. Its system of action is very reliable and functional: it can directly and incredibly feed on a selection of reactive oxygen and nitrogen species and has a solid steel ion chelating ability. Specifically, its special sulfhydryl group develops an inert complicated with copper ions, efficiently stopping these metal ions from militarizing the production of more harmful cost-free radicals. In addition, studies have discovered that it binds to a specific transporter protein, OCTN1, within cells. This transporter can exactly supply ergothioneine to areas of high oxidative tension and energy demand, like an express delivery solution, guaranteeing its optimum safety efficacy.
| Melting point | 275-277°C (dec.) |
| density | 1.2541 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | -20°C |
| solubility | Soluble in Water (up to 10 mg/ml) |
| form | White solid. |
| pka | 1.706±0.32(predicted) |
| color | White or off-white |
| PH | +47^o (c=1 in water) |
| biological source | fungus (Actinomycetales) fungus (Ascomycota) fungus (Basidiomycota) |
| Water Solubility | water: 50mg/mL, clear, colorless |
Directory Guidance on L-Ergothioneine
⇒We provide high-purity chemical raw materials with clear molecular formula and precise specifications. Each batch of L-Ergothioneine products undergoes strict quality inspection to ensure stable and reliable physical and chemical properties. It adopts international standard packaging, sealed and moisture-proof, to ensure safe transportation and storage. Whether it is R&D experiments or industrial production, we can provide you with professional technical support and customized services. With rigorous technology, transparent data and stable supply, we help you efficiently complete chemical applications and innovations.
The broad application potential customers of L-Ergothionene are rooted in its powerful and multifunctional cellular protective device. Whether in the field of skincare as a “guardian angel” against environmental damages, in the field of nourishment as an “inherent keystone” for preserving body organ function, or in the field of medicine as a “prospective new star” for combating chronic conditions, its core values are reflected in its unmatched antioxidant efficacy, anti-inflammatory buildings, and special mobile transport system, making it a key bioactive molecule attaching health, elegance, and long life science.
L-Ergothionene is known as the “brand-new generation of gold antioxidant standard”. Its excellence hinges on its ability to supply a multi-level cellular degree defense beyond standard antioxidant components. It not only effectively counteracts responsive oxygen types such as singlet oxygen and peroxynitrite in the environment, however additionally has antioxidant capacity far going beyond many traditional parts. Via its one-of-a-kind “activation regrowth” device, it can help recover the task of other vital antioxidants (such as vitamin C and E) in cells, forming a powerful interior antioxidant network. Furthermore, it has actually been shown to dramatically lower DNA damage in skin cells triggered by ultraviolet radiation and prevent the transmission of inflammatory signals, therefore synergistically delaying signs of aging and enhancing general skin wellness and luster from numerous dimensions of anti-oxidant, anti-aging, and anti-inflammatory results.
As a cellular degree physiological protective agent, the value of L-Ergothionene is progressively noticeable. As a result of the lack of ability of the human body to synthesize by itself, it becomes important to eat through diet plan or supplements. It is very concentrated in the body, particularly in high energy consuming body organs such as the liver, eye lens, and mind, imitating a “cell sentinel” that constantly shields proteins, lipids, and DNA in these delicate tissues from oxidative damages. Study has actually revealed that enough degrees of ergotamine are carefully pertaining to maintaining cognitive health and wellness, safeguarding aesthetic function, and supporting liver detoxification feature. For that reason, utilizing it as a nutritional supplement intends to boost the body’s antioxidant protection capacity at the systemic degree, fight persistent swelling and age-related functional decrease, and is a critical financial investment focused on long-lasting health and wellness.
L-Ergothionene has actually shown excellent potential worth, and its research study has actually much exceeded the standard antioxidant classification. Scientists are discovering its restorative capacity in neurodegenerative illness such as Alzheimer’s and Parkinson’s, as it can go across the blood-brain barrier and shield nerve cells from oxidative stress and mitochondrial dysfunction. At the same time, its function in managing inflammatory feedback and cell survival paths likewise makes it a study object for dealing with chronic inflammation associated diseases such as inflammatory bowel condition and metabolic disorder. More advanced research study recommends that it might play an essential function in postponing the overall aging process and boosting immune feature by protecting immune cells and keeping telomere size.
Related References
Manufacturer of L-Ergothioneine
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional L-Ergothioneine manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
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