Name：L-Tert-Leucine
Cas:20859-02-3
Purity: 99%
MOQ: 1KG
L-tert-Leucine is a non natural chiral amino acid, with the chemical name (S) -2-amino-2,3-dimethylbutyric acid. The alpha carbon atom in its molecular structure is linked to a tert butyl team, and this unique steric obstacle effect offers its side chains a high level of steric barrier and chemical inertness. This structural function causes substantial differences in its physical and chemical residential properties compared to common healthy protein amino acids, such as displaying unique polarity, solubility, and conformational stability. It typically exists in the form of white crystalline powder and is not easily associated with traditional enzymatic biosynthesis reactions.
From the viewpoint of stereochemistry, L-tert-Leucine particles include chiral centers with an absolute S-shaped setup. This certain spatial setup makes it an essential structural device in chiral synthesis. Due to the strong steric barrier result of its side chain tert butyl, the particle exhibits considerable rigidity in conformation, efficiently limiting the rotational freedom of adjacent chemical bonds. This structural characteristic makes it a suitable version compound for discovering stereo impacts, molecular acknowledgment, and structure-activity relationships in basic chemical research study, giving a distinct research study perspective for understanding intermolecular communications.
| Melting point | ≥300 °C (lit.) |
| alpha | 6.3 º (c=4, 6 N HCl 200 ºC) |
| Boiling point | 217.7±23.0 °C(Predicted) |
| density | 1.1720 (estimate) |
| refractive index | -9 ° (C=3, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 1 M HCl: 50 mg/mL |
| form | powder |
| pka | 2.39±0.12(Predicted) |
| color | White to almost white |
| Optical Rotation | [α]20/D 9.5°, c = 3 in H2O |
| Water Solubility | 125.5 g/L (20 ºC) |
Directory Guidance on L-Tert-Leucine
⇒We provide high-purity chemical raw materials with clear molecular formula and precise specifications. Each batch of L-Tert-Leucine products undergoes strict quality inspection to ensure stable and reliable physical and chemical properties. It adopts international standard packaging, sealed and moisture-proof, to ensure safe transportation and storage. Whether it is R&D experiments or industrial production, we can provide you with professional technical support and customized services. With rigorous technology, transparent data and stable supply, we help you efficiently complete chemical applications and innovations.
L-Tert Leucine has actually advanced from a straightforward non natural amino acid to a flexible player spanning both life sciences and physical scientific researches. It plays the function of a “stabilizer” and “booster” in drug store, a “chiral amplifier” in artificial chemistry, and a “structure director” in materials science. Its extensive application throughout multiple disciplinary areas deeply symbolizes the core scientific principle that molecular framework determines product function, and continues to promote advancement and advancement of cutting-edge modern technologies.
The value of L-tert-Leucine far exceeds that of a normal amino acid block. Its core benefit hinges on the reality that the tert butyl group on the side chain forms a big spatial protective umbrella. This strong steric limitation effect can significantly prevent the method and attack of proteases on peptide bonds, thereby dramatically enhancing the metabolic security of peptide medicines and lengthening their half-life in vivo. For example, it can effectively resist the degradation of different plasma enzymes by presenting it right into complicated anticancer peptides or long-term GLP-1 analogues for the therapy of diabetic issues. At the same time, this rigid side chain can secure the conformation of surrounding amino acids, minimize the versatility of the polypeptide chain, and exactly manage the communication between drugs and target proteins (such as receptors or enzymes), enhancing selectivity and efficacy. It is the front runner approach for creating “peptide like” molecules.
L-tert-Leucine is an all-natural chiral treasure and an excellent beginning factor for manufacturing high-end chiral stimulants. Drug stores utilize it as a chiral design template to construct a collection of exceptionally structured and high-performance chiral ligands via chemical alteration, such as oxazoline drivers, P, N-type chiral phosphine ligands, etc. These drivers can act as exact chiral “molds” in crucial responses such as uneven hydrogenation, cyclopropanation, and carbon bond formation, guiding reactants to bind in details spatial alignments and generating almost solitary chiral items with extremely high enantioselectivity, giving an eco-friendly and effective technical path for the synthesis of chiral medicines, scents, and functional natural particles.
L-Tert Leucine is coming to be a motivation for developing smart biomimetic products. The researchers used it as a core foundation, which was installed into polymer chains or supramolecular gel networks. Its enormous tert butyl group not only successfully avoids the limited packing of polymer chains through the physical “wedging” impact, thereby managing the crystallinity and mechanical buildings of the material, yet likewise generates the development of details helical frameworks or chiral spatial arrangements throughout the system via chiral transfer. This exact molecular design can be made use of to make fluid crystal products with chiral recognition and separation functions, very selective adsorption membrane layers, and also soft robot actuators that can create macroscopic deformation feedbacks to external stimuli such as light and pH, showing a terrific connection from molecular chirality to macroscopic feature.
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Manufacturer of L-Tert-Leucine
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional L-Tert-Leucine manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
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