Name:Liquiritigenin
Cas: 578-86-9
Purity: 99%
MOQ: 1KG
Liqiritigenin is a natural organic compound extracted from the dried rhizomes of traditional Chinese medicine licorice, and belongs to the dihydroflavonoid subtype of flavonoids in chemical classification. It is one of the most representative core active substances in licorice flavonoids. Its chemical structure is characterized by two benzene rings connected by an oxygen-containing heterocyclic ring, and functional groups such as hydroxyl groups are attached at specific positions. This unique molecular skeleton is the structural basis for its various biological activities.
This property is also commonly used in its separation and purification processes. As a natural product, Liquiritigenin has relatively stable chemical properties, but the phenolic hydroxyl groups in its structure also make it sensitive to light, heat, and oxidative environments. Its stable existence and structure-activity relationship have always been important topics in plant chemistry and natural product chemistry research.
| Melting point | 206-208°C |
| Boiling point | 529.5±50.0 °C(Predicted) |
| density | 1.386±0.06 g/cm3(Predicted) |
| Fp | 207℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO : 125 mg/mL (487.80 mM; Need ultrasonic) |
| form | powder |
| pka | 7.71±0.40(Predicted) |
| color | White |
Directory Guidance on Liquiritigenin
⇒We provide high-purity chemical raw materials with clear molecular formula and precise specifications. Each batch of Liquiritigenin products undergoes strict quality inspection to ensure stable and reliable physical and chemical properties. It adopts international standard packaging, sealed and moisture-proof, to ensure safe transportation and storage. Whether it is R&D experiments or industrial production, we can provide you with professional technical support and customized services. With rigorous technology, transparent data and stable supply, we help you efficiently complete chemical applications and innovations.

Liquiritigenin with its complex and diverse biological activities, has achieved a magnificent transformation from traditional medicinal herbs to modern multi domain core functional ingredients. It is deepening from “basic anti-inflammatory” to “neuroprotection” and other cutting-edge fields in medicine; A systematic solution for upgrading from “single whitening” to “multi-channel skincare” in cosmetics; In the food industry, it has evolved from “providing sweetness” to a comprehensive raw material that combines flavor and health. This process not only reflects the profound chemistry of natural products, but also perfectly interprets how to empower the wisdom of ancient plants in all aspects of human health and a better life through modern technology.
The value of Liquiritigenin goes far beyond its basic anti-inflammatory and antioxidant properties. In depth research has revealed that it can precisely inhibit the production of pro-inflammatory cytokines through multiple signaling pathways, such as the NF – κ B pathway, providing a new approach for the treatment of chronic inflammatory diseases. Its antioxidant mechanism not only clears free radicals, but also upregulates the body’s own antioxidant enzyme system (such as superoxide dismutase SOD), achieving dual effect cell protection. In addition, the potential of Liquiritigenin in neuroprotection is being actively explored. Studies have shown that it may have a positive impact on the prevention and treatment of neurodegenerative diseases such as Alzheimer’s disease by inhibiting neuroinflammation and oxidative damage, demonstrating its enormous potential as a multi-target natural drug.
The application of Liquiritigenin has been upgraded from a single functional ingredient to a multifunctional composite active substance. In terms of whitening, it not only inhibits tyrosinase, but also interferes with the transport of melanocytes from the dermis to the epidermis, thereby achieving a “multi link” blockade of the melanin pathway. Its soothing ability has also been deeply understood, and it has been proven to effectively reduce the levels of key inflammatory factors such as interleukins in the skin, quickly alleviating immediate redness and discomfort caused by UV radiation, chemical stimulation, etc. Therefore, it has become an indispensable core ingredient in high-end “cosmetics” and sensitive skin specific products, working together with other active ingredients to build a healthy ecosystem for the skin.
Liquiritigenin is no longer just a sweetener, but a “flavor architect”, and “natural preservative”. The unique sweet release curve of Liqiritigenin – the characteristic that first slows down and then lasts – is used in order to balance out the metallic aftertaste of beverages with low sugar or sugar-free sweeteners, bringing the flavor closer to sucrose. Liquiritigenin is used in the meat processing industry to not only extend shelf life but also increase meat flavor and aroma through Maillard reactions with amino acids. Its long-lasting sweetness and antibacterial properties in chewing gums and candies prevent dental caries. Snack foods are given a healthier connotation.
Related References
Manufacturer of Liquiritigenin
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Liquiritigenin manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Company Info
Cooperation Partner
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