Name: Methylfolate
Cas: 134-35-0
Purity: 99%
MOQ: 1KG
Directory Guidance on Methylfolate
Chemical Structure

Basic Info
Methylfolate is an active type of folic acid (Folic Acid, Vitamin B9), with the chemical name 5-methyltetrahydrofolate (5-MTHF). Its common salt kinds consist of calcium salt (L-5-MTHF-Ca) and glucosamine salt (L-5-MTHF-Glucosamine), which have much better water solubility and bioavailability and are extensively used in medication, food supplements and cosmetics. Its molecular formula is normally shared as C20H25N7O6 (cost-free form), which can straight join the folic acid metabolic path in the body without additional enzymatic conversion, so it is simpler to be absorbed and made use of by the human body than common folic acid.
In terms of biochemical action, methylfolate is a vital element of the one-carbon metabolic rate pathway, mostly made use of to provide methyl groups to support DNA and RNA synthesis, amino acid metabolic rate and homocysteine(Hcy) conversion. Because some people may have folate metabolic process problems as a result of MTHFR gene mutations, methylfolate, as an activated kind of folate, is preferable as a nutritional supplement for this team of individuals.
Product Introduction
| Melting point | >300°C (dec.) |
| density | 1.62±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Aqueous Base (Slightly, Sonicated) |
| form | Solid |
| pka | 3.51±0.10(Predicted) |
| color | Pale Beige |
| MF: | C20H25N7O6 |
| MW: | 459.46 |
| EINECS: | 603-809-2 |
| Item | Specification |
| Product Name | Methylfolate |
| CAS No. | 134-35-0 |
| Appearance | powder |
| Shelf Life | 2 years |
| Packing | As your requirements |
Product Packaging
1. Medication and nutritional supplements
Methylfolate (generally 5-methyltetrahydrofolate L-5-MTHF) is the energetic type of folic acid (vitamin B9), which can straight take part in the body’s one-carbon metabolic rate, assistance DNA synthesis, healthy protein metabolic rate and natural chemical manufacturing. Therefore, it has essential applications in the fields of medication and nutritional supplements:
Folic acid deficiency treatment: It appropriates for individuals with folic acid metabolism problems caused by MTHFR genetics anomalies. It is much easier to soak up than common folic acid and is commonly utilized as a nutritional supplement for pregnant ladies, anemia people and people with neurological diseases.
Cardiovascular wellness: Methylfolate can decrease homocysteine( Hcy) degrees and help in reducing the threat of atherosclerosis, heart disease and stroke.
Supporting treatment of clinical depression: As an active form of folic acid, methylfolate can boost the synthesis of serotonin, dopamine and norepinephrine, and aid in antidepressant medication therapy.
2. Functional foods and dietary fortification
Due to its high bioavailability, methylfolate is commonly used in useful foods and dietary fortification items, consisting of:
Baby formula: sustains neural tube growth of fetuses and babies and minimizes the threat of neural tube issues.
Fortified foods: such as cereals, power bars, drinks, etc, to improve the effectiveness of folic acid intake.
Nutritional supplements: utilized alone or in mix with B vitamins to boost vitamins and mineral absorption.
3. Cosmetics and skin care products
Methylfolate has a great effect on skin cell repair work and anti-oxidation, so it is made use of in skin care items:
Advertise skin cell repair work: boost epidermal cell DNA synthesis, speed up the skin repair work process, and is suitable for anti-aging and trauma repair work products.
Antioxidant result: can decrease free extreme damage, enhance skin obstacle feature, and stop photoaging.
Whitening skin care: by regulating pigment metabolic rate, minimizing melanin manufacturing, making the skin color much more also.
4. Drugs and Biotechnology
Drug raw materials: Methylfolate can be utilized as an energetic pharmaceutical active ingredient (API) for the treatment of folate-related illness, such as megaloblastic anemia, persistent inflammatory diseases, and so on.
Microencapsulation modern technology: In pharmaceutical preparations and food additives, methylfolate is often used in microencapsulation or nanoemulsification technology to boost stability and continual release effects and maximize absorption performance.
Related References
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Choose us, you will experience:
Excellent quality: products meet international standards, stability and purity are verified multiple times.
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Please contact us now for more product details and exclusive quotes. Let us become your only choice for chemical raw material procurement and open a new chapter of cooperation together!
Manufacturer of Methylfolate
Zhishang Chemical is based in Shandong, serves the whole country, faces the world, and is determined to become an excellent supplier and service provider in the chemical industry.
As a top manufacturer of cosmetic raw materials, disinfectants, flavors and fragrances in China, we are committed to producing high-quality products and have won high praise from customers all over the world.
In the next 10 years or even longer, Zhishang will always adhere to the tenet of quality first and reputation first, and devote itself to providing customers with thoughtful and perfect services.
As a professional Methylfolate manufacturer, Zhi shang Chemical has served more than 6,000 customers around the world. Because of our high-quality products and professional services, we have won high praise from most of our customers.
Pre-Sales Service
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
After-Sales Service
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
DO YOU ACCEPT SAMPLE ORDER?
We will make samples before mass production. After the samples are approved by the department and users, we will start mass production. During the production process, we will carry out 100% inspection, and then carry out random inspection before packaging.
WHAT’S YOUR MOQ?
Our MOQ is 1kg. But usually we can also accept a smaller quantity, such as 100g, if you need it, provided that the sample fee is 100% paid.
IS THERE A DISCOUNT?
Different quantity has different discount.
HOW TO CONFIRM WHETHER THE PRODUCT QUALITY MEETS OUR NEEDS BEFORE PLACING AN ORDER?
You can consult us to get free samples of some products, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us the product specifications and requirements you need, and we will manufacture products according to your requirements.
DO YOU SUPPLY PRODUCT REPORT?
Yes. We’ll give you product analysis report before shipping.
LEARN MORE ABOUT US
Shandong Look Chemical
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





