High-Purity N-Acetyl-L-cysteine (NAC) Supplier | CAS 616-91-1 | Zhishang Chem
Name: N-Acetyl-L-Cysteine
Cas:616-91-1
Purity: 99%
MOQ: 1KG
Directory Guidance on N-Acetyl-L-Cysteine
Chemical Structure
Basic Info
| Melting point | 106-108 °C(lit.) |
| alpha | -35.1 ºC (c=2,H2O) |
| Boiling point | 407.7±40.0 °C(Predicted) |
| bulk density | 730kg/m3 |
| density | 1.249 (estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 24 ° (C=JPC Method) |
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL with heating |
| pka | pK1: 9.52 (30°C) |
| form | Solid |
| color | White |
| PH | 1.5-2.5 (20°C, 100g/L in H2O) |
| biological source | rabbit |
In the highly sensitive pharmaceutical and nutraceutical fields, product safety, regulatory alignment, and source traceability are non-negotiable requirements for global market distribution. Zhishang Chem ensures that every batch of N-Acetyl-L-cysteine satisfies strict international regulatory frameworks, facilitating seamless compliance audits for your brand:
- Pharmacopeia Standard Alignment:Our material rigorously complies with the latest monographs of the United States Pharmacopeia (USP) and European Pharmacopoeia (EP).
- ISO 9001:2015 Certification:Our complete industrial manufacturing chain, from raw material validation to final crystal milling and automated packaging, operates under a verified quality management system.
- Kosher & Halal Certified Ready:Manufactured via a 100% animal-free, synthetic fermentation-derivative pathway. The production lines are strictly monitored to ensure zero cross-contamination, making it suitable for strict vegan and religious-compliant product lines.
- Global Export Documentation Package:To expedite customs clearance, we supply complete GHS-compliant Safety Data Sheets (SDS), TSE/BSE-Free Statements, Allergen-Free Declarations, and non-GMO certification with every bulk contract.
Product Packaging
Thanks to its robust cellular protective mechanism and reactive chemistry, our N-Acetyl-L-cysteine acts as a multi-functional powerhouse across three primary industries:
- Dietary Supplements & Nutraceuticals:Extensively utilized as a foundational antioxidant raw material in liver detoxification complexes, respiratory health formulas, and cellular longevity ingredient It works by replenishing intracellular glutathione stores to combat systemic oxidative stress.
- Cosmetics & Anti-Aging Skincare:Actively formulated in premium topical serums, brightening creams, and skin barrier balms. NAC safely interrupts the tyrosinase activation cascade, effectively reducing melanin synthesis while boosting skin elasticity through dermal tissue protection.
- Pharmaceutical Formulations:Deployed as a reliable mucolytic agent in cough remedies and a vital stabilizer for various complex molecular structures.
- Critical Formulation Tips:
- Moisture & Oxygen Sensitivity:NAC powder is highly hygroscopic and susceptible to air oxidation. Final blending should be carried out under low-humidity conditions (RH < 40%) using inert gas purging if possible.
- Incompatibility:Avoid direct contact with iron, copper, rubber, or alkaline substances. We recommend utilizing stainless steel (316L Grade) or glass-lined machinery during mixing. Incorporating chelating agents like citric acid or EDTA can further protect the active sulfhydryl groups from breakdown.
FAQ
A: Our standard commercial packaging for buy NAC powder bulk orders is a heavy-duty 25kg fiber drum lined with dual anti-static, heat-sealed PE inner bags to block moisture and eliminate powder dispersion during plant handling. For research institutes or indie brands conducting bench-scale optimization, we can provide specialized 1kg or 5kg aluminum foil bags as a trial MOQ.
A: Many commercial entities operate strictly as traders, compounding market price spikes and logistics delays. As an integrated amino acid derivatives supplier, Zhishang Chem maintains extensive, long-term upstream supply agreements for core raw materials. By maximizing manufacturing throughput and automating the crystallization loop, we bypass intermediate trade markups, enabling us to guarantee a highly stable, competitive wholesale NAC price even during periods of global supply chain volatility.
Related References
Pubchem-N-Acetyl-L-Cysteine
Chemicalbook-N-Acetyl-L-Cysteine
Self-Inspection & Quality Control (Strict Purity & Trace Metal Standards)
Because trace metallic impurities or moisture can accelerate the oxidation of active sulfhydryl groups into ineffective disulfides, Zhishang Chem enforces an rigorous, multi-tiered self-inspection strategy within our analytical testing center:
- Assay Purity (by High-Performance Liquid Chromatography / Titration):0% to 101.0% (Calculated on the dried substance).
- Specific Optical Rotation:+21.0° to +27.0° (Verifying absolute isomeric purity and elimination of D-enantiomers).
- State of Solution (Transmittance):≥ 95.0% Minimum (Ensuring a perfectly clear, sediment-free liquid phase when dissolved).
- Heavy Metals & Arsenic Restrictions:Total heavy metals (as Pb) ≤ 10 ppm; Arsenic (As) ≤ 1 ppm; Iron (Fe) ≤ 10 ppm. (Crucial for preventing catalytic oxidation in wet formulations).
- Loss on Drying:≤ 0.5% Maximum.
- Residue on Ignition:≤ 0.1% Maximum.
- Traceability Promise: We completely eliminate commodity trade uncertainty. An authentic, batch-tied Certificate of Analysis (COA) generated by our advanced laboratory accompany every physical shipment, ensuring the chemical metrics perfectly align with your high-standard processing requirements.
Manufacturer of N-Acetyl-L-Cysteine
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
