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Manufacturer Neohesperidin Dihydrochalcone CAS 20702-77-6

  • Payment: L/C,T/T,D/P,Paypal,Money Gram,Western Union
  • Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
  • Min: 10 Gram
  • Delivery: 7 Days
  • Transporta: Ocean, Land,Air, DHL,TNT
  • Port: Shanghai Port, Qingdao Port

Name: Neohesperidin Dihydrochalcone

Cas: 20702-77-6

Purity: 99%

MOQ: 1KG

Basic Info

Neohesperidin Dihydrochalcone, NHDC, abbreviated as NHDC in English, is a flavonoid compound originated from natural citrus plants. It does not directly expand in plants, however is made from neohesperidin removed from citrus peel through chemical processes such as ring opening and catalytic hydrogenation. The chemical formula of this substance isC28H36O15, with a molecular weight of 612.58. At space temperature level, it looks like white or somewhat yellow grainy crystals with a fairly routine look.
 
From the viewpoint of physical and chemical residential properties, the most prominent feature of Neohesperidin Dihydrochalcone is its incredibly high sweet taste, which has to do with 1500-1800 times sweeter than sucrose, and its calorie content is especially reduced. The reason is that the glycosidic groups it includes do not join metabolic rate in the human body and do not bring excess warmth problem to the body. Its pleasant release rhythm is different from that of sucrose. After entering the mouth, the sweetness comes slowly, however the aftertaste is long-lasting, and the preference is freshening without the pain of sweetness.
 
In regards to security, Neohesperidin Dihydrochalcone additionally performs well. Its properties are steady at room temperature level, and as long as the pH worth is above 2, it can preserve its initial characteristics in acidic or alkaline environments, even under heat problems. It is challenging to go through hydrolysis reactions and will not lose its sweet taste, making it ideal for various processing circumstances. In addition, NHDC additionally has lots of physical activities and superior antioxidant effects. Relevant studies have also located that it has certain protective capacity for the liver.

Product Introduction

Melting point 156-158 °C(lit.)
Boiling point 927.1±65.0 °C(Predicted)
density 1.61±0.1 g/cm3(Predicted)
vapor pressure 0Pa at 20℃
FEMA 3811 | NEOHESPERIDIN DIHYDROCHALCONE
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Practically insoluble in water, freely soluble in dimethyl sulfoxide, soluble in methanol, practically insoluble in methylene chloride.
pka6.85±0.40(Predicted)
form crystalline
color light yellow
Odorat 100.00 %. bland odor
Odor Typeodorless
biological sourcesynthetic
Water Solubility Insoluble

 

Product Packaging

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Thanks to its distinct physical and chemical homes and sensible physical activity, Neohesperidin Dihydrochalcone has a significantly large range of application circumstances. It is not just a premium high magnifying sweetener, however likewise a functional active ingredient with numerous biological tasks. Its application scope has already expanded past the conventional food sector and progressively broadened to multiple fields such as medication, cosmetics, and clinical research study, with encouraging development leads.

In the food industry, Neohesperidin Dihydrochalcone is mainly made use of as a functional sugar. The qualities of ultra-high sweetness and ultra-low calorie allow it to satisfy the sweet demands of diabetes individuals and obese individuals, and is likewise suitable for developing sugar totally free and reduced sugar foods. In addition to giving a wonderful preference, it can additionally successfully mask the bitter preference in food, maximize the total taste, and boost the eating experience.

Neohesperidin Dihydrochalcone is rarely made use of alone and is mostly utilized in combination with other sweeteners such as acesulfame and sucralose. By leveraging the synergistic impact of sweetness, it can achieve a pure taste better to sucrose and make food structure a lot more perfect. Taking sugar totally free yogurt as an instance, maximizing the NHDC compound plan with scientific proportioning can not only make certain the taste and flavor of yogurt fulfill the requirements, however additionally replace sucrose to the best degree feasible; However, it needs to be noted that if the amount included goes beyond the requirement, it may lengthen the fermentation time of yogurt and minimize its viscosity. It is needed to manage the amount used.

In the fields of medicine and health-related, the numerous physiological tasks of Neohesperidin Dihydrochalcone have additionally gotten interest. Existing research has actually confirmed that NHDC can prevent pancreatic lipase activity, which indicates it has specific application worth in managing fat absorption and assisting weight management. At the same time, its antioxidant residential or commercial properties have likewise been very valued by the market, and multiple research study reviews have discussed its possible application area in the pharmaceutical area.
 
In sophisticated study, researchers likewise fluorescently identify Neohesperidin Dihydrochalcone, such as coupling it with FITC, to develop molecular probes that combine all-natural task and visualization functions. These probes are made use of to track medicine shipment procedures, research mobile uptake systems, or check out the concepts of natural products, providing practical study devices for pharmacology research study and nanocarrier growth.
In the cosmetics sector, Neohesperidin Dihydrochalcone has ended up being a preferred skincare ingredient because of its outstanding bleaching effect. It can effectively prevent the task of tyrosinase, which is the crucial enzyme for melanin manufacturing and decreases melanin accumulation at the root. In vitro speculative data shows that the half maximal repressive concentration (IC50) of NHDC on tyrosinase is 82.02 μ m/L, and the inhibitory effect is also better than numerous traditional whitening agents.
 
Based upon this device of action, Neohesperidin Dihydrochalcone is commonly included in whitening skincare solutions. There are also related patents showing that intensifying NHDC and Polygonum multiflorum extract in a proportion of 8:1 to 10:1 can apply a synergistic whitening effect and considerably improve the bleaching and area lightening impact of the item. In addition, the preliminary human examination also showed that the gel preparation added with NHDC can boost the melasma with certain impact and safety and security.

Along with working as fluorescent identified probes, Neohesperidin Dihydrochalcone itself is likewise a crucial focus of natural product chemistry research study. For instance, in the associated research study of Eucommia ulmoides, researchers will certainly use technologies such as high-performance fluid chromatography to precisely identify the specific web content of NHDC in Eucommia ulmoides leaves from various origins and development years. They will additionally examine its correlation with environment and dirt problems such as latitude, annual typical temperature level, soil level of acidity and alkalinity, and raw material web content. This type of research can aid people understand the adjustments in plant active components and offer trusted scientific recommendations for screening high-quality seed resources and regulating planting.

Related References

Manufacturer of Neohesperidin Dihydrochalcone

Company Info

Zhishang chemical company in China that exports chemicals, Cosmetic raw materials, and Intermediates for over 70 countries now.
 
And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

Cooperation Partner

Raymond
I would like to thank Shandong Zhishang New Materials Co., Ltd. for a very efficient transaction with their team.
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Raymond Louis
The goods have been delivered intact. good packing. honest seller
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Mary
As usual, a great service from dear zhishang chemical, and the perfect quality of product! Highly recommend this company, and hope for long and productive cooperation :)
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