Zinc Gluconate (CAS 4468-02-4) Manufacturer & Supplier | USP/BP Standard High Purity Powder
Name: Zinc Gluconate
Cas: 4468-02-4
Purity: 99%
MOQ: 1KG
Directory Guidance on Zinc Gluconate
Chemical Structure
Basic Info
Zinc Gluconate (CAS 4468-02-4): Premium Bioavailable Zinc Source for Dietary Supplements, Pharmaceuticals, and Personal Care
Zinc Gluconate (Zinc D-gluconate, dihydrate/anhydrous form) is the zinc salt of gluconic acid, renowned for its superior bioavailable profile and high water solubility relative to inorganic zinc sources. Produced through the controlled neutralization of gluconic acid with high-purity zinc oxide, this organic chelate presents as a white to off-white crystalline powder with a neutral to slightly astringent taste profile.
As an essential trace element provider, Zinc Gluconate is widely selected by pharmaceutical formulators, nutraceutical brands, and personal care manufacturers due to its gentle.
| Melting point | 172-175 °C |
| Boiling point | 319°C |
| density | 1.44[at 20℃] |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Store at -20°C |
| solubility | Soluble in water, practically insoluble in anhydrous ethanol and in methylene chloride. |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Soluble in water 100g/ l. |
To meet global regulatory mandates for pharmaceutical excipients, dietary ingredients, and cosmetic additives, our production facility adheres to international compliance standards.
GMP & ISO Standards: Produced in cleanroom environments compliant with GMP principles and ISO 22000 / ISO 9001 certified quality management systems.
Pharmacopeial Monograph Compliance: Fully tested to conform with United States Pharmacopeia (USP), European Pharmacopoeia (EP), and British Pharmacopoeia (BP) monographs.
Food Safety & Dietary Certification: Certified Kosher and Halal; non-GMO verified, and free from animal-derived materials (suitable for vegan formulations).
Regulatory Documentation: Comprehensive regulatory support packages available upon request, including Safety Data Sheets (SDS according to GHS), Certificate of Analysis (COA), Allergen Statements, Heavy Metals Analysis, and BSE/TSE-Free Declarations.
Product Packaging
Every batch of Zinc Gluconate undergoes rigorous multi-stage analytical testing in our ISO 17025 accredited laboratory to ensure batch-to-batch consistency and high chemical purity.
Assay & Zinc Content Determination: Complexometric titration using disodium edetate (EDTA) to accurately measure zinc content within the tight 97.0% – 102.0% range.
Heavy Metals & Elemental Impurities: Screened using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to guarantee strict adherence to stringent safety limits (Lead, Arsenic, Cadmium, and Mercury within ultra-trace thresholds).
Reducing Substances & Limit of Chloride/Sulfate: Wet chemical pharmacopeial limit tests conducted to prevent unwanted side-reactions in sensitive formulations.
pH & Solubility Evaluation: Verified in a 1.0% aqueous solution (pH range 5.5 to 7.5) to confirm rapid dissolution and formulation compatibility.
Microbial Limits Testing: Total Aerobic Microbial Count (TAMC), Total Yeast and Mold Count (TYMC), and pathogen screening (E. coli, Salmonella) performed to ensure oral-grade safety.
Zinc Gluconate is a versatile ingredient deployed across diverse industrial sectors:
Dietary Supplements & Nutraceuticals: Primary active component in tablets, hard capsules, effervescent powders, softgels, and oral lozenges designed for trace mineral supplementation.
Pharmaceutical Formulations: Utilized in oral liquid solutions, rehydration mixtures, and specialized medical nutrition formulations requiring reliable zinc bioavailability.
Personal Care & Cosmetics: Integrated into topical skin formulations, anti-acne serums, and soothing creams to aid skin surface conditioning and sebum balance.
Oral Care Products: Added to toothpastes and mouthwashes as a active agent to help control bad breath and maintain oral hygiene.
Formulation & Processing Notes:
Solubility: Highly soluble in water; practically insoluble in alcohol and organic solvents.
Stability: Stable under ambient dry storage conditions; compatible with most standard processing excipients when protected from excessive heat and direct moisture.
FAQ
A: Zinc Gluconate offers significantly higher aqueous solubility and better biological absorption compared to insoluble forms like Zinc Oxide. Additionally, organic gluconate chelates typically exhibit milder gastrointestinal tolerance and a less harsh metallic taste than inorganic zinc salts like Zinc Sulfate.
A: Fine powders (e.g., 80-100 mesh) are ideal for homogeneous blending in dry beverage mixes, sachets, and cosmetic emulsions. Granular grades provide improved flowability and lower dust creation during direct compression tableting operations.
A: The material is supplied in standard 25 kg fiber drums with double-layer polyethylene inner liners. Store in tightly closed containers in a cool, dry, well-ventilated warehouse, away from incompatible strong oxidizing agents and moisture.
Related References
Pubchem-Zinc Gluconate
Chemicalbook-Zinc Gluconate
Manufacturer of Zinc Gluconate
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
