Polyquaternium-10 (CAS 81859-24-7) Supplier & Manufacturer | Cosmetic Grade Cationic Cellulose
Name: Polyquaternium-10
Cas: 81859-24-7
Purity: 99%
MOQ: 1KG
Directory Guidance on Polyquaternium-10
Chemical Structure

Basic Info
Polyquaternium-10 (CAS No. 81859-24-7) is a quaternized hydroxyethyl cellulose derivative widely utilized as a multifunctional conditioning agent, thickener, and rheology modifier in personal care formulations. Featuring a polymeric backbone derived from natural cellulose, this water-soluble cationic polymer carries positive charges that readily adhere to negatively charged keratin proteins found on human hair and skin surfaces.
In modern cosmetic chemistry, Polyquaternium-10 functions without leaving heavy, greasy residues. It provides smooth wet combability, detangling performance, static control, and rich lather stabilization across a broad pH range (3.0 – 8.0). Designed to meet strict industrial specifications, our product serves as a direct, high-performance alternative to standard market grades such as JR-400, LR-400, and JR-30M.
| Melting point | 290 °C(lit.) |
| Cosmetics Ingredients Functions | FILM FORMING ANTISTATIC |
| EPA Substance Registry System | Cellulose, 2-hydroxyethyl 2-[2-hydroxy-3-(trimethylammonio)propoxy]ethyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride (81859-24-7) |
To support global export and ensure smooth regulatory approval for international personal care brands, our Polyquaternium-10 manufacturing processes adhere strictly to standardized global chemical control systems:
ISO 9001:2015 Quality Management System: Standardized production control ensuring batch-to-batch consistency in viscosity and charge density.
ISO 14001 & ISO 45001 Compliance: Environmentally responsible manufacturing and safe occupational health standards.
EU REACH Registered / Compliant: Fully documented for compliant importation into European Union member states.
Halal & Kosher Statements: Processed without animal-derived raw materials; suitable for halal and vegan personal care lines.
Safety & Heavy Metal Standards: Complies with EU Cosmetics Regulation (EC) No 1223/2009 and US FDA cosmetic safety parameters regarding trace heavy metals and residual monomers.
Product Packaging
Every commercial batch of Polyquaternium-10 undergoes rigid internal Quality Control (QC) before release. Our analytical laboratories utilize validated testing methods to guarantee physical and chemical parameters:
Nitrogen Content Analysis (Kjeldahl Method): Verifies the exact degree of cationicity (quaternization), ensuring reliable conditioning performance and static reduction on hair shafts.
Viscosity Measurement (Brookfield Viscometer): Evaluated at 20°C/25°C in a 1% or 2% aqueous solution to ensure precise flow control and thickening capability in shampoo formulations.
Loss on Drying (Moisture Testing): Maintained under strict limits (≤ 6.0%) to prevent clumping during storage and ensure accurate formulation dosing.
Ash & Heavy Metal Analysis (AAS/ICP-MS): Measures trace lead, arsenic, mercury, and cadmium to comply with global toxicological safety margins for topical applications.
Microbiological Testing: Plate count testing ensures Total Aerobic Microbial Count (TAMC) and Total Yeasts/Moulds Count (TYMC) remain well below international cosmetic standards (< 100 CFU/g), free from Pseudomonas aeruginosa and Staphylococcus aureus.
Polyquaternium-10 exhibits excellent compatibility with anionic, non-ionic, amphoteric, and cationic surfactants. It is widely applied across personal care sectors:
Hair Care Formulations (Shampoos, Conditioners, Hair Masks)
Wet & Dry Combing Improvement: Forms a thin protective film over hair cuticles, significantly reducing friction, breakage, and split ends.
Anti-Static & Anti-Frizz: Neutralizes negative charges on hair strands, controlling flyaways in dry or humid conditions.
Lather Enhancement: Enhances foam stability and creates a creamy texture in clear or sulfate-free shampoo systems.
Recommended Dosage: 0.1% – 0.8%
Skin Care & Body Washes
Moisture Retention & Skin Feel: Imparts a velvety, non-sticky after-feel to body washes, liquid hand soaps, and shaving creams.
Surfactant Harshness Mitigation: Reduces skin tightness caused by primary surfactants.
Recommended Dosage: 0.05% – 0.3%
Formulation Tip: To avoid lump formation during hydration, slowly sprinkle Polyquaternium-10 into room-temperature water while stirring vigorously. Adjusting the pH to slightly acidic levels (pH 5.5–6.5) helps accelerate full hydration and clarification of the solution.
FAQ
A: Polyquaternium-10 is derived from a natural cellulose backbone, offering superior film-forming, thickening, and moisture retention properties, making it ideal for clear shampoos and restorative hair treatments. Polyquaternium-7 is a synthetic acrylamide copolymer primarily used for basic conditioning in rinse-off cleansing products.
A: Sulfate-free surfactants often struggle with foam density and hair feel. Polyquaternium-10 boosts foam viscosity, improves lather creaminess, and provides the necessary slip and combability that consumers expect.
A: No. Polyquaternium-10 forms a water-soluble, breathable film that washes off easily during regular cleansing routines, preventing the heavy buildup often associated with insoluble silicones.
A: It is standardly packed in 25 kg fiber drums or multi-ply paper bags with moisture-proof PE inner liners. Store in a cool, dry, well-ventilated warehouse away from direct sunlight and moisture to maintain a shelf life of 24 months.
Related References
Pubchem-Polyquaternium-10
Chemicalbook-Polyquaternium-10
Manufacturer of Polyquaternium-10
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.





